Electrochemotherapy in Veterinary Oncology
Electropermeabilization is a method that uses electric field pulses to induce an electrically mediated reorganization of the plasma membrane of cells. Electrochemotherapy combines local or systemic administration of chemotherapeutic drugs such as bleomycin or cisplatin that have poor membrane permeability with electropermeabilization by direct ...
M, Cemazar +7 more
openaire +2 more sources
Electrochemotherapy induces apoptotic death in melanoma metastases: A histologic and immunohistochemical investigation [PDF]
Background: Electrochemotherapy (ECT) is increasingly used in the treatment of primary and secondary skin tumors, but little is known about the pathologic mechanism responsible for tumor cell destruction in humans. Knowledge of detailed mechanism of host
BIGI, Laura +6 more
core +2 more sources
Therapeutic potential of bleomycin plus suicide or interferon-β gene transfer combination for spontaneous feline and canine melanoma [PDF]
We originated and characterized melanoma cell lines derived from tumors of two feline and two canine veterinary patients. These lines reestablished the morphology, physiology and cell heterogeneity of their respective parental tumors.
Agnetti, Lucrecia +4 more
core +1 more source
Effectiveness of electrochemotherapy after IFN-α adjuvant therapy of melanoma patients
The combination of electrochemotherapy with immuno-modulatory treatments has already been explored and proven effective. However, the role of interferon alpha (IFN-α) adjuvant therapy of melanoma patients and implication on electrochemotherapy ...
Hribernik Andrejc +4 more
doaj +1 more source
Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma [PDF]
BACKGROUND: Interleukin-12 (IL-12) based radiosensitization is an effective way of tumor treatment. Local cytokine production, without systemic shedding, might provide clinical benefit in radiation treatment of sarcomas.
Ales Sedlar +5 more
core +1 more source
Tumor size and effectiveness of electrochemotherapy [PDF]
Electrochemotherapy (ECT) is an effective and safe method for local treatment of tumors. However, relatively large variability in effectiveness of ECT has been observed, which likely results from different treatment conditions and tumor characteristics.
Mali, B +6 more
openaire +4 more sources
Electroporation is used in cancer treatment because of its ability to increase local cytotoxicity of e.g. bleomycin (electrochemotherapy) and calcium (calcium electroporation).
Hanne Falk +6 more
doaj +1 more source
Electrochemotherapy as a treatment option for feline nasal melanoma
Case summary A 4-year-old domestic shorthair cat presented to North Downs Specialist Referrals for treatment of a 7 mm melanoma of the nasal planum.
Annika Little, Michael Macfarlane
doaj +1 more source
The effect of high-frequency electric pulses on tumor blood flow in vivo [PDF]
The aim of this study was to evaluate the effect of a 5-kHz repetition frequency of electroporating electric pulses in comparison to the standard 1-Hz frequency on blood flow of invasive ductal carcinoma tumors in Balb/C mice.
Firoozabadi, S. +4 more
core +1 more source
Electrochemotherapy for the treatment of an incompletely excised subcutaneous low grade epithelioid hemangioendothelioma in a budgerigar parakeet (Melopsittacus undulatus) [PDF]
Background: Cutaneous tumors are rarely described in avians, and are frequently of viral origin. Solid tumors of vascular origin are seldom reported and usually result in a difficult management by surgery alone.
Andrea Lanza +3 more
doaj +1 more source

