Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1983 The anticancer drug, bleomycin, has recently been shown to be light-sensitive by a number of research groups. This photosensitivity extends to its complexes with iron(II), copper(II), cobalt(III) and DNA. Nicking of DNA by photoactivated bleomycin occurs at lower concentrations than under dark conditions.
Douglas, K. T.; id_orcid
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Bleomycin resistance conferred by a drug-binding protein
FEBS Letters, 1988 The protein coded by a bleomycin-resistance gene (ble) cloned from producing actinomycetes was purified from a culture of a recombinant E.coli strain and its action on bleomycin was determined by in vitro assays.
Anne Gatignol +2 more
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The influence of tramadol and parecoxib on erythmyocin or bleomycin-induced pleurodesis in rabbit: a pilot study [PDF]
, 2021 Introduction: Recurrent pleural effusion secondary to advanced malignant diseases can lead to poor quality of life, recurrent hospital stays and increased hospital costs, which has yet to be extensively explored.
Nik Amin Sahid Nik Lah +6 more
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Cancer, 1967 Bleomycin A, which is a complex of water-soluble peptides produced by a Streptomyces, inhibits DNA synthesis in intact cells of E. coli and HeLa cells and also inhibits Ehrlich carcinoma and Sarcoma 180. When it is injected, it distributes in lung and skin at higher concentration than in blood and kidney.
H, Umezawa +3 more
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Magnetic resonance imaging as a non-invasive tool to investigate pulmonary and renal fibrosis in small rodents : method and readout validation, animal model optimization, and substance testing [PDF]
, 2015 Pulmonary fibrosis, an end result of various types of lung damage including interstitial pneumonia and respiratory bronchiolitis (Gross and Hunninghake, 2001; Katzenstein and Myers, 1998; Lazenby et al., 1990) is a lethal disease characterized by ...
Egger, Christine
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Lung fibrosis 10 years after cessation of bleomycin therapy. [PDF]
, 2008 Bleomycin (BLM) is a chemotherapeutic agent used for the treatment of several types of malignancy, including germ cell tumors, lymphoma, and certain types of squamous-cell carcinoma.
Yanagihara, Katunori +14 more
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Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis [PDF]
, 2011 Background The balancing functions of pro/anti-inflammatory mediators of the complex innate responses have been investigated in a variety of experimental inflammatory settings. Annexin-A1 (AnxA1) is one mediator of endogenous anti-inflammation, affording
Amílcar S Damazo +25 more
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Transarterial embolization with bleomycin for symptomatic hepatic focal nodular hyperplasia [PDF]
, 2017 PURPOSE:We aimed to evaluate the therapeutic effect and safety of transarterial embolization using bleomycin-iodinated oil and polyvinyl alcohol particles for the treatment of symptomatic hepatic focal nodular hyperplasia (FNH).METHODS:This retrospective
Guodong Zhang +6 more
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Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]
, 2000 Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
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Bleomycin-induced pulmonary fibrosis in mouse lungs.
, 2017 (A) Images of lungs from mice that were either subject to nasal administration of methylene blue (right) or not (left).
Yuko Yamada (3749758) +5 more
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