Results 1 to 10 of about 402,746 (187)
Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases.
Deming Li +5 more
doaj +1 more source
Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias [PDF]
, 2015 Background Pulmonary hypertension (PH) is a common finding in patients with chronic fibrosing idiopathic interstitial pneumonias (IIP). Little is known about the response to pulmonary vasodilator therapy in this patient population.
Behr, Juergen +19 more
core +22 more sources
Nos2 deficiency enhances carbon tetrachloride-induced liver injury in aged mice [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): As a multifunctional molecule, NO has different effects on liver injury. The present work aimed to investigate the effects of Nos2 knockout (KO) on acute liver injury in aged mice treated with carbon tetrachloride (CCl4).
Deming Li +7 more
doaj +1 more source
BMC Medical Education, 2022 Background The purpose of the National Health and Medical Research Council Centre of Research Excellence in Pulmonary Fibrosis (CRE-PF) is to improve and extend the lives of patients living with pulmonary fibrosis through the development of a ...
Katherine Christian +7 more
doaj +1 more source
[Idiopathic pulmonary fibrosis].
Medecine sciences : M/S, 2022 38;6 ...
Hennion, Nathan +4 more
+9 more sources
La Presse Médicale, 2023 Idiopathic pulmonary fibrosis (IPF) is a progressive devastating lung disease with substantial morbidity. It is associated with cough, dyspnea and impaired quality of life. If left untreated, IPF has a median survival of 3 years. IPF affects ∼3 million people worldwide, with increasing incidence in older patients. The current concept of pathogenesis is
Thomas Koudstaal, Marlies S. Wijsenbeek
openaire +2 more sources
Scientific Reports, 2023 Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease that causes irreversible damage to lung tissue characterized by excessive deposition of extracellular matrix (ECM) and remodeling of lung parenchyma.
Zhongzheng Li +8 more
doaj +1 more source
Cell Communication and Signaling, 2023 Background Matrix metalloproteinases (MMPs) play important roles in remodeling the extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF).
Weiming Zhao +11 more
doaj +1 more source
Idiopathic pulmonary fibrosis [PDF]
Orphanet Journal of Rare Diseases, 2008 Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation. IPF is a rare disease which affects approximately 5 million persons worldwide.
Noble Paul W, Meltzer Eric B
openaire +3 more sources
Fat storage-inducing transmembrane proteins: beyond mediating lipid droplet formation
Cellular & Molecular Biology Letters, 2022 Fat storage-inducing transmembrane proteins (FITMs) were initially identified in 2007 as members of a conserved endoplasmic reticulum (ER) resident transmembrane protein gene family, and were found to be involved in lipid droplet (LD) formation. Recently,
Gaiping Wang +5 more
doaj +1 more source