Results 11 to 20 of about 402,863 (300)

Idiopathic pulmonary fibrosis

Medicina Clínica (English Edition), 2017
Idiopathic pulmonary fibrosis is a fibrosing interstitial pneumonia associated with the radiological and/or histological pattern of usual interstitial pneumonia. Its aetiology is unknown, but probably comprises the action of endogenous and exogenous micro-environmental factors in subjects with genetic predisposition.
Antoni, Xaubet, Julio, Ancochea, María, Molina-Molina   +2 more
exaly   +10 more sources

Idiopathic pulmonary fibrosis [PDF]

Thorax, 2011
Idiopathic pulmonary fibrosis is a progressive lung disease that carries a poor prognosis and for which there are no effective therapies. Although the excessive deposition of extracellular matrix, combined with evidence of recurrent injury to the alveolar epithelium, are well-described there is a pressing need to understand these processes better at a ...
Zhe Hui, Hoo, Moira K B, Whyte
exaly   +6 more sources

ADRB2 inhibition combined with antioxidant treatment alleviates lung fibrosis by attenuating TGFβ/SMAD signaling in lung fibroblasts

Cell Death Discovery, 2023
Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease with a poor prognosis and limited therapeutic options, which is characterized by aberrant myofibroblast activation and pathological remodeling of the extracellular matrix,
Ruyan Wan, Lan Wang, Yudi Duan, Miaomiao Zhu, Wenwen Li, Mengxia Zhao, Hongmei Yuan, Kai Xu, Zhongzheng Li, Xiao Zhang, Guoying Yu   +10 more
doaj   +1 more source

Pulmonary Fibrosis [PDF]

, 2005
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease limited to the lungs and associated with the histologic appearance of usual interstitial pneumonia (UIP) on surgical lung biopsy. The estimated prevalence in the United States is between 35,000 and 55,000 cases,and evidence suggests that the prevalence is increasing for IPF.
Zisman, David A., Keane, Michael P., Belperio, John A., Strieter, Robert M., Lynch, Joseph P.   +4 more
openaire   +2 more sources

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Adamson IY, Artinian V, Aubry MC, Bai JW, Baumgartner KB, Berschneider B, Brody AR, Chen PP, Chilosi M, Chilosi M, Coalson JJ, Corrin B, Dasari V, Dissanayake SK, Dobbs LG, Flozak AS, Fukuda Y, Ha HY, Haddad R, Herzog EL, Hironaka M, Hu J, Huang CL, Hubbard R, Huber MA, Jayachandran A, Kasai H, Kasper M, Kato N, Kawasaki H, Kawasaki H, Kim J, Kim K, Kim KK, Kuwano K, Königshoff M, Königshoff M, Königshoff M, Lee JM, Liu L, Maher TM, Margalit O, Mason RJ, Matthay MA, Mazieres J, Melanie Königshoff, Moon RT, Nagai A, Pan LH, Park J, Pennison M, Plataki M, Qunn L, Radisky DC, Rosas IO, Sato M, Selman M, Selman M, Soon LL, Sternlicht MD, Thannickal VJ, Thiery JP, Uematsu K, Willis BC, Willis BC, Willis BC, Zavadil J   +66 more
core   +1 more source

Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial [PDF]

, 2020
Compelling data have linked disease progression in patients with idiopathic pulmonary fibrosis (IPF) with lung dysbiosis and the resulting dysregulated local and systemic immune response.
A Mishra, AW Brown, B Ley, BA Karimi-Shah, BT Baxter, CJ Ryerson, DG Pankratz, DJ Lederer, G Raghu, G Raghu, H Scheper, HR Collard, J Andrade, J Coast, J Coast, K Loudon, K Loudon, KA Getz, KD Brandt, KE Thorpe, KF Schulz, L Richeldi, L Shulgina, LB Krupp, M Fralick, M Hammond, MA Fischl, MA Perazella, MO Paterniti, MT Durheim, P Bhattacharyya, PL Molyneaux, PL Molyneaux, PL Molyneaux, R Dal-Ré, RM Califf, RM du Bois, SD Nathan, SS Birring, T Katsuyama, TE King Jr, VA Varney, WS Jones, Y Huang   +43 more
core   +1 more source

Physical activity and activity space in patients with pulmonary fibrosis not prescribed supplemental oxygen

BMC Pulmonary Medicine, 2017
Background Patients with pulmonary fibrosis (PF) have impaired quality of life, and research suggests that dyspnea and physical activity are primary drivers. As PF progresses, some patients notice the disease “shrinks their worlds”. The objective of this
Elisabeth Dowling Root, Bridget Graney, Susan Baird, Tara Churney, Kailtin Fier, Majorie Korn, Mark McCormic, David Sprunger, Tomas Vierzba, Frederick S. Wamboldt, Jeffery J. Swigris   +10 more
doaj   +1 more source

A Case Report of Systemic Sclerosis Complicated by Biventricular Heart Failure, Pulmonary Hypertension and Review of Literature [PDF]

, 2017
Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder whose aetiology is not fully understood. Skin fibrosis and visceral organs involvement are the hallmarks, and the heart could be disproportionately or subtly involved ...
Akinboro AO, Akinlade M, Akintunde AA, Audu MB   +3 more
core   +1 more source

Tracking dyspnea up to supplemental oxygen prescription among patients with pulmonary fibrosis

BMC Pulmonary Medicine, 2017
Background Dyspnea is the hallmark symptom of pulmonary fibrosis. Supplemental oxygen (O2) is prescribed to many patients with pulmonary fibrosis in hopes of alleviating dyspnea and improving physical functioning.
Amy L. Olson, Bridget Graney, Susan Baird, Tara Churney, Kaitlin Fier, Marjorie Korn, Mark McCormick, David Sprunger, Thomas Vierzba, Frederick S. Wamboldt, Jeffrey J. Swigris   +10 more
doaj   +1 more source

Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly

Respiratory Research, 2023
Background Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease (ILD) with unknown etiology, characterized by sustained damage repair of epithelial cells and abnormal activation of fibroblasts, the underlying mechanism of the ...
Caoyuan Niu, Kai Xu, Yanan Hu, Yanling Jia, Yuexia Yang, Xiaoyue Pan, Ruyan Wan, Hui Lian, Qiwen Wang, Juntang Yang, Yajun Li, Ivan Rosas, Lan Wang, Guoying Yu   +13 more
doaj   +1 more source