Bioengineering, 2022 The increasing number of life-threatening infections observed in cancer patients has been ascribed to chemotherapy-induced neutropenia and to invasive medical procedures such as surgery and the application of catheters.
Carla C. C. R. de Carvalho
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Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis [PDF]
Frontiers in PharmacologyIntroductionChemotherapeutic agents, despite their toxicities, variability in individual response, and risk of drug-drug interactions, are essential in the treatment of gastrointestinal cancers.
Robert Siegel +6 more
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Application of Optical Methods for Determination of Concentration of Doxorubicin in Blood and Plasma
Pharmaceuticals, 2022 The aim of presented research is to develop a simple and quick method of spectrophotometric detection for the determination of doxorubicin hydrochloride in blood and plasma.
Tomasz Sikora +4 more
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Analysis of 12 cases of antineoplastic agents-induced interstitial lung disease
Frontiers in Pharmacology, 2023 Objective: To summarize the situation of antineoplastic agents-induced interstitial lung diseases (ILD), provide reference for strengthening clinical management of druginduced interstitial lung diseases (DILD).Methods: We retrospectively investigated the
Xiao Li +4 more
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Antineoplastics Encapsulated in Nanostructured Lipid Carriers
Molecules, 2021 Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays, with well-defined therapeutic protocols.
Gustavo Henrique Rodrigues da Silva +6 more
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A case-control study of Clostridioides difficile symptomatic infections in a pediatric cancer hospital [PDF]
Revista Paulista de Pediatria, 2023 Objective: The aim of this study was to analyze and identify documented infections and possible risk factors for Clostridioides difficile infections in children with cancer. Methods: This is a retrospective case-control study, carried out in a pediatric
Adriana Maria Paixão de Sousa da Silva +10 more
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Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes
Frontiers in Microbiology, 2022 Natural products from actinomycetes serve as a crucial source of clinical pharmaceuticals, especially antibiotics and anticancer agents. Among them, polycyclic xanthones belong to a growing group of highly oxygenated aromatic polyketides with a xanthone ...
Hui-Qing Yu +3 more
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Influence of fullerenol C60(OH)24 on enzime status in serum of rats after single dose administration of doxorubicine [PDF]
Hemijska Industrija, 2008 The antracycline antibiotics have one of the widest areas of use in oncology. The most investigated mechanisms of their antineoplastic activity include: interactions of these antibiotics with DNA, inhibition of topoisomerase II and production of free ...
Govedarica Biljana Č. +4 more
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Ceftazidime and cefepime antagonize 5-fluorouracil’s effect in colon cancer cells
BMC Cancer, 2022 Background Drug-drug interaction (DDI), which can occur at the pharmacokinetics and/or the pharmacodynamics (PD) levels, can increase or decrease the therapeutic or adverse response of a drug itself or a combination of drugs.
Christina Pfab +6 more
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Biological screening of a unique drug library targeting MRGPRX2
Frontiers in Immunology, 2022 BackgroundAllergic drug reaction or drug allergy is an immunologically mediated drug hypersensitivity reaction (DHR). G-protein coupled receptors (GPCRs) are common drug targets and communicate extracellular signals that initiate cellular responses ...
Fan Yang +8 more
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