Inhibition of the MRSA Biofilm Formation and Skin Antineoplastic Activity of Ethyl Acetate Roots and Aerial Parts Extracts from Geum urbanum L. [PDF]
AntibioticsBackground: The opportunistic pathogen Staphylococcus aureus causes skin and soft tissue infections that are associated with biofilm formation, and in immunocompromised patients can progress to surgical site infections, pneumonia, bacteremia, sepsis, and
Lyudmila Dimitrova +5 more
doaj +4 more sources
Adaptation of Bacteria to Antineoplastic Agents Involves Persister Cells and Increases Resistance to Antibiotics [PDF]
Bioengineering, 2022 The increasing number of life-threatening infections observed in cancer patients has been ascribed to chemotherapy-induced neutropenia and to invasive medical procedures such as surgery and the application of catheters.
Carla C. C. R. de Carvalho
doaj +2 more sources
Analysis of 12 cases of antineoplastic agents-induced interstitial lung disease [PDF]
Frontiers in Pharmacology, 2023 Objective: To summarize the situation of antineoplastic agents-induced interstitial lung diseases (ILD), provide reference for strengthening clinical management of druginduced interstitial lung diseases (DILD).Methods: We retrospectively investigated the
Xiao Li +4 more
doaj +3 more sources
Application of Optical Methods for Determination of Concentration of Doxorubicin in Blood and Plasma [PDF]
Pharmaceuticals, 2022 The aim of presented research is to develop a simple and quick method of spectrophotometric detection for the determination of doxorubicin hydrochloride in blood and plasma.
Tomasz Sikora +4 more
doaj +2 more sources
Drug induced hyperpigmentation: systematic review and meta-analysis [PDF]
Frontiers in MedicineBackgroundDrug-induced hyperpigmentation (DIH) represents a significant subset of acquired pigmentation disorders and poses diagnostic challenges due to delayed onset and polypharmacy.
Ruaa Alharithy +8 more
doaj +2 more sources
Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis [PDF]
Frontiers in PharmacologyIntroductionChemotherapeutic agents, despite their toxicities, variability in individual response, and risk of drug-drug interactions, are essential in the treatment of gastrointestinal cancers.
Robert Siegel +6 more
doaj +2 more sources
Antineoplastics Encapsulated in Nanostructured Lipid Carriers
Molecules, 2021 Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs) are available nowadays, with well-defined therapeutic protocols.
Gustavo Henrique Rodrigues da Silva +6 more
doaj +1 more source
A case-control study of Clostridioides difficile symptomatic infections in a pediatric cancer hospital [PDF]
Revista Paulista de Pediatria, 2023 Objective: The aim of this study was to analyze and identify documented infections and possible risk factors for Clostridioides difficile infections in children with cancer. Methods: This is a retrospective case-control study, carried out in a pediatric
Adriana Maria Paixão de Sousa da Silva +10 more
doaj +1 more source
Isolation, Biosynthesis, and Biological Activity of Polycyclic Xanthones From Actinomycetes
Frontiers in Microbiology, 2022 Natural products from actinomycetes serve as a crucial source of clinical pharmaceuticals, especially antibiotics and anticancer agents. Among them, polycyclic xanthones belong to a growing group of highly oxygenated aromatic polyketides with a xanthone ...
Hui-Qing Yu +3 more
doaj +1 more source
Influence of fullerenol C60(OH)24 on enzime status in serum of rats after single dose administration of doxorubicine [PDF]
Hemijska Industrija, 2008 The antracycline antibiotics have one of the widest areas of use in oncology. The most investigated mechanisms of their antineoplastic activity include: interactions of these antibiotics with DNA, inhibition of topoisomerase II and production of free ...
Govedarica Biljana Č. +4 more
doaj +1 more source