Results 21 to 30 of about 22,504 (303)
Intracellular acidification is a hallmark of thymineless death in E. coli.
PLoS Genetics, 2022 Thymidine starvation causes rapid cell death. This enigmatic process known as thymineless death (TLD) is the underlying killing mechanism of diverse antimicrobial and antineoplastic drugs.
Alexandra Ketcham +2 more
doaj +1 more source
Desensitization for the prevention of drug hypersensitivity reactions [PDF]
The Korean Journal of Internal Medicine, 2022 Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang +2 more
doaj +1 more source
An overview of diagnosis and management of drug‐induced hypomagnesemia
Pharmacology Research & Perspectives, 2021 Magnesium (Mg) is commonly addressed as the “forgotten ion” in medicine. Nonetheless, hypomagnesemia should be suspected in clinical practice in patients with relevant symptomatology and also be considered a predisposing factor for the development of ...
George Liamis +3 more
doaj +1 more source
Comprehensive Analysis of Chemotherapeutic Agents That Induce Infectious Neutropenia
Pharmaceuticals, 2021 Chemotherapy-induced neutropenia (CIN) has been associated with a risk of infections and chemotherapy dose reductions and delays. The chemotherapy regimen remains one of the primary determinants of the risk of neutropenia, with some regimens being more ...
Mashiro Okunaka +4 more
doaj +1 more source
Adjunctive Impact of Mitochondria-Targeting Antibiotics for Cancer Stem Cells of Oral Squamous Cell Carcinoma: Proposal for a Novel Approach in Resistant Cases [PDF]
Journal of DentistryDear SirOral Squamous Cell Carcinoma (OSCC) is the most common cancer involving the oral and maxillofacial area [1]. OSCC is reported to exert the worst quality of life among the patients suffering from head and neck cancers [2].
Mohammad Amin Amiri +3 more
doaj +1 more source
International Journal of Medical Microbiology, 2023 There has been an explosion in the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) because of the indiscriminate use of antibiotics. In this study, we repurposed hexestrol (HXS) as an antibacterial agent to fight planktonic and biofilm ...
Shasha Liu +7 more
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A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem [PDF]
Exploration of Drug ScienceThe presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of antibiotics, endocrine disruptors, and other ...
Jaya Vinny Eapen +4 more
doaj +1 more source
Frontiers in Chemistry, 2022 Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have previously identified a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich type complexes with bidentate monosaccharide ligands possessing ...
Bence Balázs +11 more
doaj +1 more source
Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. [PDF]
PLoS Genetics, 2008 Inner ear sensory hair cell death is observed in the majority of hearing and balance disorders, affecting the health of more than 600 million people worldwide.
Kelly N Owens +8 more
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Chronic candidal osteomyelitis of mid face: A therapeutic dilemma
Journal of Oral Biology and Craniofacial Research, 2013 Numerous explanations have been proposed for the increase in fungal infections including the use of broad-spectrum antibiotics, antineoplastic agents and prosthetic devices.
Rishi Bali +3 more
doaj +1 more source