Results 21 to 30 of about 22,637 (303)

Comprehensive Analysis of Chemotherapeutic Agents That Induce Infectious Neutropenia

open access: yesPharmaceuticals, 2021
Chemotherapy-induced neutropenia (CIN) has been associated with a risk of infections and chemotherapy dose reductions and delays. The chemotherapy regimen remains one of the primary determinants of the risk of neutropenia, with some regimens being more ...
Mashiro Okunaka   +4 more
doaj   +1 more source

Desensitization for the prevention of drug hypersensitivity reactions [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2022
Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang   +2 more
doaj   +1 more source

Adjunctive Impact of Mitochondria-Targeting Antibiotics for Cancer Stem Cells of Oral Squamous Cell Carcinoma: Proposal for a Novel Approach in Resistant Cases [PDF]

open access: yesJournal of Dentistry
Dear SirOral Squamous Cell Carcinoma (OSCC) is the most common cancer involving the oral and maxillofacial area [1]. OSCC is reported to exert the worst quality of life among the patients suffering from head and neck cancers [2].
Mohammad Amin Amiri   +3 more
doaj   +1 more source

Antibacterial and antibiofilm efficacy of repurposing drug hexestrol against methicillin-resistant Staphylococcus aureus

open access: yesInternational Journal of Medical Microbiology, 2023
There has been an explosion in the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) because of the indiscriminate use of antibiotics. In this study, we repurposed hexestrol (HXS) as an antibacterial agent to fight planktonic and biofilm ...
Shasha Liu   +7 more
doaj   +1 more source

Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer : a multicentre prospective randomized trial [PDF]

open access: yes, 2009
Background The effect of additional treatment strategies with antineoplastic agents on intraperitoneal tumor stimulating interleukin levels are unclear.
Willems Wilhelm   +13 more
core   +1 more source

A new cytotoxic phenylthiazoline, 4-methylaeruginoic acid, from Streptomyces sp. KCTC 9303 [PDF]

open access: yes, 1997
4 methylaeruginoic acid; cytotoxic agent; phenylthiazoline derivative; unclassified drug; antibiotic biosynthesis; article; carbon nuclear magnetic resonance; physical chemistry; priority journal; proton nuclear magnetic resonance; streptomyces ...
Ick Dong Yoo   +5 more
core   +1 more source

Bactericidal Effect of Combinations of Antibiotic and Antineoplastic Agents against Staphylococcus aureus and Escherichia coli. [PDF]

open access: yes, 2002
Background: The bactericidal effect of some antibiotic and antineoplastic agents commonly used in clinical practice was investigated to analyse whether the combinations act synergistically, have indifferent or antagonistic antibacterial effects compared ...
Nilsson-Ehle, Ingrid   +3 more
core   +1 more source

A review of the effects of pharmaceutical pollutants on humans and aquatic ecosystem [PDF]

open access: yesExploration of Drug Science
The presence of high-quality water is essential not only for human survival but also for the well-being of plants and animals. This research aimed to examine studies investigating the occurrence of antibiotics, endocrine disruptors, and other ...
Jaya Vinny Eapen   +4 more
doaj   +1 more source

Targeting Multiresistant Gram-Positive Bacteria by Ruthenium, Osmium, Iridium and Rhodium Half-Sandwich Type Complexes With Bidentate Monosaccharide Ligands

open access: yesFrontiers in Chemistry, 2022
Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have previously identified a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich type complexes with bidentate monosaccharide ligands possessing ...
Bence Balázs   +11 more
doaj   +1 more source

Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. [PDF]

open access: yesPLoS Genetics, 2008
Inner ear sensory hair cell death is observed in the majority of hearing and balance disorders, affecting the health of more than 600 million people worldwide.
Kelly N Owens   +8 more
doaj   +1 more source

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