Results 31 to 40 of about 62,115 (257)
Delayed onset bleomycin-induced pneumonitis
, 2005 We describe a 39-year-old male patient who developed bleomycin-induced pneumonitis 2 years after completion of chemotherapy for nonseminomatous testicular cancer.
Uzel, B +7 more
core +1 more source
Lung fibrosis 10 years after cessation of bleomycin therapy. [PDF]
, 2008 Bleomycin (BLM) is a chemotherapeutic agent used for the treatment of several types of malignancy, including germ cell tumors, lymphoma, and certain types of squamous-cell carcinoma.
Yanagihara, Katunori +14 more
core +1 more source
Flagellate dermatitis in a patient with testicular germ cell neoplasia on bleomycin
Dermatology Reports, 2023 Bleomycin, an antineoplastic antibiotic that inhibits DNA synthesis, is used to treat various malignant tumours such as Hodgkin's lymphoma, squamous cell carcinoma, and germ cell tumors.
Konstantina Mavridou +4 more
doaj +1 more source
Studies on the mechanism of action of the chemotherapeutic drug bleomycin on cell lines derived from haemangioma and keloid [PDF]
, 2009 Bleomycin has been used successfully in the treatment of haemangioma, keloid and vascular malformation; however the mode of action of this chemotherapeutic drug on these non-malignant dysplasias is not well understood.
Clarke, Lisa
core
DNA Interaction with 57Co-Bleomycin
, 1982 Tumor-diagnostic 57Co-bleomycin is a mixture of two isomers: types I and II. Interaction between these and DNA was studied by fluorescence spectrometry and thermal denaturation.
H. Orii, J. Kakinuma
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Effects of rapamycin on bleomycin induced fibrosis and autophagy.
, 2013 Hydroxyproline assay measuring lung collagen content demonstrates co-administration of rapamycin and bleomycin protects against fibrosis (*p = 0.003 for control vs. bleomycin; **p = 0.008 for bleomycin vs. rapamycin + bleomycin).
Alexander Geyer (315474) +7 more
core +1 more source
Spontaneous pneumomediastinum caused by bleomycin-induced pneumonitis [PDF]
, 2012 peer reviewedWe report the case of a 24-yr-old woman treated for lymphoma who developed bleomycin-induced intersitial pneumonia. This interstitial pneumonia was complicated by spontaneous pneumomediastinum.
Beguin, Yves +6 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Bleomycin and scuba diving:where is the harm?
, 2007 Testicular cancer is the most frequent malignant disease in men aged 15–40 years. Due to its sensitivity to chemotherapeutic drugs, most patients, including those with widespread metastatic disease, can now be cured.
Sleijfer, Stefan +10 more
core +1 more source