Treatment outcomes of AIDS-associated Kaposi's sarcoma under a routine antiretroviral therapy program in Lilongwe, Malawi: bleomycin/vincristine compared to vincristine monotherapy. [PDF]
PLoS ONE, 2014 Despite Kaposi's sarcoma (KS) being the most prevalent AIDS-associated cancer in resource limited settings, optimal treatment options remain unknown.
Albert A Mwafongo +7 more
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Biomedicines, 2022 The Red Sea marine fungus Penicillium chrysogenum (Family: Ascomycota) comprises a panel of chemically diverse natural metabolites. A meleagrin alkaloid was isolated from deep-sediment-derived P.
Sameh S. Elhady +9 more
doaj +1 more source
Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging. [PDF]
, 2017 Intestinal stem cells (ISCs) maintain the midgut epithelium in Drosophila melanogaster Proper cellular turnover and tissue function rely on tightly regulated rates of ISC division and appropriate differentiation of daughter cells.
Abramov +68 more
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Vascular sclerosing effects of bleomycin on cutaneous veins: a pharmacopathologic study on experimental animals [PDF]
Anais Brasileiros de Dermatologia, 2017 : Background: Varicose veins and the complications of venous disease are common disorders in humans. Objective: To study the effects of bleomycin as a potential new sclerosing agent and its adverse events in treating varicose veins. Methods: Bleomycin-
Khalid M AlGhamdi +5 more
doaj +2 more sources
Basal cell carcinoma: 10-year experience with electrochemotherapy [PDF]
, 2017 BACKGROUND: Electrochemotherapy (ECT), by combining manageable cytotoxic agents with short electric pulses, represents an effective palliative skin-directed therapy.
Alaibac, MAURO SALVATORE ALESSANDRO +6 more
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Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): The role of N-acetylcysteine (NAC) as an anti-oxidant in attenuating bleomycin-induced pulmonary fibrosis has been reported. However, its effect on parenchymal remodeling via regulating the protease-antiprotease balance is not fully defined.
Ritu Kulshrestha +3 more
doaj +1 more source
Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution. [PDF]
, 2017 Thy-1-negative lung fibroblasts are resistant to apoptosis. The mechanisms governing this process and its relevance to fibrotic remodeling remain poorly understood. By using either sorted or transfected lung fibroblasts, we found that Thy-1 expression is
Bradley, John E +11 more
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Frontiers in Bioengineering and BiotechnologyIntroductionTargeted delivery of anticancer drugs holds great promise for enhancing therapeutic efficacy while minimizing adverse effects. The folate receptor (FR)-mediated approach offers a selective strategy to target cancer cells overexpressing FR ...
Elham Saberian +10 more
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Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
, 2015 Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
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Management of germ cell tumors in children: Approaches to cure [PDF]
, 2002 The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G. +4 more
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