Results 51 to 60 of about 53,368 (224)
Characterization of Bleomycin-Resistant DNA
, 1973 After reaction of DNA with high concentrations of bleomycin, approximately 80% of the DNA becomes trichloroacetic acid (TCA) soluble. The remaining 20% of the DNA remains TCA insoluble.
Kuo, M.Tien +2 more
core +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
Andrology, EarlyView.ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
, 1976 Results from treating 51 patients with advanced esophageal cancer are presented. Fifteen patients were treated with Bleomycin, 12 with radiotherapy, and 24 with a combination of Bleomycin and radiotherapy.
Ivo Dujmović +3 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Testicular cancer (TC) is the most common malignancy amongst adolescents and young adults (AYAs) aged 15–39 years assigned male at birth. Survivors often experience late effects of treatment and report unmet supportive care needs.
Mohamad M. Saab +30 more
wiley +1 more source
Malignant Ovarian Germ Cell Tumor-Survival and Reproductive Outcomes and Patterns of Relapse. [PDF]
Cancer MedBLURB FOR ETOC: Patients presenting with advanced MOGCT can be offered fertility‐sparing surgery after neoadjuvant chemotherapy with no detriment in oncological outcome. ABSTRACT Background Malignant ovarian germ cell tumors [MOGCT] are rare cancers affecting young women and often present in advanced stages.
Dey S +24 more
europepmc +2 more sources
Photolabelling of dopamine-β-hydroxylase by bleomycin
, 1983 Irradiation of a mixture of dopamine-β-hydroxylase and bleomycin with light of wavelengths >300 nm. leads to irreversible inhibition which is not prevented in the presence of tyramine.
Ratwatte, Hiran A.M. +1 more
core +1 more source
Reproductive outcomes in women with Hodgkin's lymphoma in a Danish fertility preservation cohort
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.The risk of premature ovarian insufficiency increases with the intensity of alkylating chemotherapy. In general, fertility outcomes were favorable, but chances of live birth decreased with increased intensity of alkylating chemotherapy. Ovarian tissue transplantation enabled natural conception in women with premature ovarian insufficiency, supporting ...
Lotte Berdiin Colmorn +4 more
wiley +1 more source
Bleomycin induced skin rashes- a case report
, 2020 Bleomycin is a cytotoxic glycopeptide derived from Streptomyces verticillus and is used in ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine) chemotherapy regimen. Bleomycin is effective against several
S. Sirisha +4 more
core
Total Synthesis of Deamido Bleomycin A2, the Major Catabolite of the Antitumor Agent Bleomycin
, 2016 Metabolic inactivation of the antitumor antibiotic bleomycin is believed to be mediated exclusively via the action of bleomycin hydrolase, a cysteine proteinase that is widely distributed in nature.
Sidney M. Hecht (1305729) +4 more
core +1 more source