Results 11 to 20 of about 45,095 (219)

Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model

open access: yesMolecules, 2023
Bleomycin, which is widely used as an antitumor agent, possesses serious adverse effects such as pulmonary toxicity. Local nanoaerosol deposition for lung cancer treatment is a promising alternative to drug delivery to lung lesions.
Saida S. Karshieva   +8 more
doaj   +1 more source

Partial omission of bleomycin for early‐stage Hodgkin lymphoma patients treated with combined modality therapy: Does incomplete ABVD lead to inferior outcomes?

open access: yeseJHaem, 2020
Classical Hodgkin lymphoma (HL) patients achieve excellent outcomes; therefore, treatment de‐escalation strategies to spare toxicity have been prioritized.
Jillian R. Gunther   +12 more
doaj   +1 more source

Bleomycin induced urethral stricture in Hodgkin′s disease

open access: yesIndian Journal of Urology, 2009
Bleomycin is a glycoprotein that is extensively used in combination with other anti-cancer agents because of its relative lack of hematological and gastrointestinal toxicity. However, pulmonary toxicity is common with bleomycin and limits its therapeutic
Ritesh Tapkire   +2 more
doaj   +1 more source

Intralesional bleomycin for treatment of a recalcitrant wart in an immunocompromised patient: A safe, effective, and underutilized therapy

open access: yesClinical Case Reports, 2022
Injectable bleomycin is infrequently used for recalcitrant warts despite its efficacy, acceptable safety profile, and high patient satisfaction compared with other treatment modalities.
Tracy Ngo   +3 more
doaj   +1 more source

Meleagrin Isolated from the Red Sea Fungus Penicillium chrysogenum Protects against Bleomycin-Induced Pulmonary Fibrosis in Mice

open access: yesBiomedicines, 2022
The Red Sea marine fungus Penicillium chrysogenum (Family: Ascomycota) comprises a panel of chemically diverse natural metabolites. A meleagrin alkaloid was isolated from deep-sediment-derived P.
Sameh S. Elhady   +9 more
doaj   +1 more source

Treatment outcomes of AIDS-associated Kaposi's sarcoma under a routine antiretroviral therapy program in Lilongwe, Malawi: bleomycin/vincristine compared to vincristine monotherapy. [PDF]

open access: yesPLoS ONE, 2014
Despite Kaposi's sarcoma (KS) being the most prevalent AIDS-associated cancer in resource limited settings, optimal treatment options remain unknown.
Albert A Mwafongo   +7 more
doaj   +1 more source

Beneficial effects of N-acetylcysteine on protease-antiprotease balance in attenuating bleomycin-induced pulmonary fibrosis in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): The role of N-acetylcysteine (NAC) as an anti-oxidant in attenuating bleomycin-induced pulmonary fibrosis has been reported. However, its effect on parenchymal remodeling via regulating the protease-antiprotease balance is not fully defined.
Ritu Kulshrestha   +3 more
doaj   +1 more source

Enhancement of bleomycin production in Streptomyces verticillus through global metabolic regulation of N-acetylglucosamine and assisted metabolic profiling analysis

open access: yesMicrobial Cell Factories, 2020
Background Bleomycin is a broad-spectrum glycopeptide antitumor antibiotic produced by Streptomyces verticillus. Clinically, the mixture of bleomycin A2 and bleomycin B2 is widely used in combination with other drugs for the treatment of various cancers.
Hong Chen   +4 more
doaj   +1 more source

Vascular sclerosing effects of bleomycin on cutaneous veins: a pharmacopathologic study on experimental animals [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Background: Varicose veins and the complications of venous disease are common disorders in humans. Objective: To study the effects of bleomycin as a potential new sclerosing agent and its adverse events in treating varicose veins. Methods: Bleomycin-
Khalid M AlGhamdi   +5 more
doaj   +2 more sources

Bleomycin-loaded folic acid-conjugated nanoliposomes: a novel formulation for targeted treatment of oral cancer

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionTargeted delivery of anticancer drugs holds great promise for enhancing therapeutic efficacy while minimizing adverse effects. The folate receptor (FR)-mediated approach offers a selective strategy to target cancer cells overexpressing FR ...
Elham Saberian   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy