Pharmaceutics, 2021 The plasma concentration profile of bleomycin in the distribution phase of patients younger than 65 years is needed to determine the suitable time interval for efficient application of electric pulses during electrochemotherapy.
Ales Groselj +9 more
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Photochemical Internalization with Fimaporfin: Enhanced Bleomycin Treatment for Head and Neck Cancer
Pharmaceutics, 2023 Head and neck squamous cell carcinoma (HNSCC) still represents the world’s sixth most common tumor entity, with increasing incidence. The reachability of light makes HNSCC suitable for light-based therapies such as Photochemical Internalization (PCI ...
Paula Enzian, Ramtin Rahmanzadeh
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Bleomycin-Induced Pulmonary Toxicity in Cancer Patients Treated at Tertiary Care Hospital
Pakistan Armed Forces Medical Journal, 2023 Objective: To report the frequency of Bleomycin-induced pulmonary toxicity in cancer patients treated with chemotherapy regimens containing Bleomycin at Combined Military Hospital, Rawalpindi Pakistan. Study Design: Case series.
Aamira Ali +5 more
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Nintedanib treatment for bleomycin-induced lung injury - First report
Respiratory Medicine Case Reports, 2023 Although the antineoplastic agent bleomycin is known for more than 50 years, its exact pharmacological and side-effect mechanisms remain incompletely understood.
Dina Rnjak +6 more
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Clinical Dermatology Review, 2023 Background: Treating of recalcitrant viral verrucae either individually or in combination is inconvenient and frustrating both for patients and treating physician. There is no treatment, which is 100% effective for warts.
Prasoon Sachan +4 more
doaj +1 more source
Administration of bleomycin via the oropharyngeal aspiration route leads to sustained lung fibrosis in mice and rats as quantified by UTE-MRI and histology. [PDF]
PLoS ONE, 2013 Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes.
Christine Egger +10 more
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Heterologous matrix metalloproteinase gene promoter activity allows In Vivo real-time imaging of Bleomycin-induced Lung fibrosis in transiently transgenized mice [PDF]
, 2017 Idiopathic pulmonary fibrosis is a very common interstitial lung disease derived from chronic inflammatory insults, characterized by massive scar tissue deposition that causes the progressive loss of lung function and subsequent death for respiratory ...
Donofrio, Gaetano +8 more
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Bleomycin-induced trans lipid formation in cell membranes and in liposome models [PDF]
, 2015 Cell cultures of NTera-2 cells incubated with bleomycin and liposomes as biomimetic models of cell membranes were used for examining some novel aspects of drug-metal induced reactivity with unsaturated lipids under oxidative conditions. In cell cultures,
Barata Vallejo, Sebastian +5 more
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Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model
Molecules, 2023 Bleomycin, which is widely used as an antitumor agent, possesses serious adverse effects such as pulmonary toxicity. Local nanoaerosol deposition for lung cancer treatment is a promising alternative to drug delivery to lung lesions.
Saida S. Karshieva +8 more
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Heparan Sulfate and Chondroitin Sulfate Glycosaminoglycans Are Targeted by Bleomycin in Cancer Cells
Cellular Physiology and Biochemistry, 2017 Background/Aims: Bleomycin is a clinically used anti-cancer drug that produces DNA breaks once inside of cells. However, bleomycin is a positively charged molecule and cannot get inside of cells by free diffusion.
Xiulian Li +11 more
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