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Prostate cancer is a complex disease that affects millions of men globally, predominantly in high human development index regions. Patients with localized disease at a low to intermediate risk of recurrence generally have a favourable outcome of 99% overall survival for 10 years if the disease is detected and treated at an early stage.
Richard J. Rebello +8 more
semanticscholar +11 more sources
This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer.
H. Sung +6 more
semanticscholar +3 more sources
MRI-targeted or standard biopsy for prostate-cancer diagnosis [PDF]
Background Multiparametric magnetic resonance imaging (MRI), with or without targeted biopsy, is an alternative to standard transrectal ultrasonography-guided biopsy for prostate-cancer detection in men with a raised prostate-specific antigen level who ...
Allen, Clare +49 more
core +2 more sources
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence and outcomes using incidence data collected by central cancer ...
R. Siegel +3 more
semanticscholar +3 more sources
Prostate cancer is the most frequent tumor found in men worldwide and in Mexico in particular. Age and family history are the main risk factors. The diagnosis is made by prostate biopsy in patients with abnormalities detected in their prostate-specific antigen (PSA) levels or digital rectal exam (DRE).
Ricardo Alonso Castillejos-Molina +1 more
+12 more sources
Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.
BACKGROUND Metastatic castration-resistant prostate cancer remains fatal despite recent advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic castration-resistant prostate cancer.
O. Sartor +19 more
semanticscholar +1 more source
Prostate Cancer, Version 4.2023, NCCN Clinical Practice Guidelines in Oncology.
The NCCN Guidelines for Prostate Cancer provide a framework on which to base decisions regarding the workup of patients with prostate cancer, risk stratification and management of localized disease, post-treatment monitoring, and treatment of recurrence ...
E. Schaeffer +37 more
semanticscholar +1 more source
Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor. [PDF]
Btk and Etk/BMX are Tec-family non-receptor tyrosine kinases. Btk has previously been reported to be expressed primarily in B cells and has an important role in immune responses and B-cell malignancies.
Bhardwaj, G +16 more
core +7 more sources
AbstractIt is a paradigm in cancer treatment that early detection and treatment improves survival. However, although screening measures lead to a higher rate of detection, for small bulk localised prostate cancer it remains unclear whether early detection and early treatment will lead to an overall decrease in mortality.
D, Mazhar, J, Waxman
openaire +4 more sources
The human gastrointestinal microbiota and prostate cancer development and treatment [PDF]
The human gastrointestinal microbiome contains commensal bacteria and other microbiota that have been gaining increasing attention in the context of cancer development and response to treatment.
Alanee +70 more
core +1 more source

