Results 41 to 50 of about 182,783 (241)

Physiological and histopathological effects of electroporation pulse on stomach of rats

BMC Gastroenterology, 2021
Background Irreversible electroporation (IRE) is an emerging tissue ablation technique with widespread potential, especially for cancer treatment. Although the safety and efficacy of IRE for gastric tissue ablation have been demonstrated, there is a gap ...
Yuchi Zhang, Xuan Han, Zhuoqun Li, Yu Zhang, Lihong Liang, Xiaoying Ma, Haonan Liu, Yihui Gao, Qingshan Li, Xue Chen, Yi Lv, Fenggang Ren   +11 more
doaj   +1 more source

Irreversible electroporation on the small intestine [PDF]

British Journal of Cancer, 2012
Non-thermal irreversible electroporation (NTIRE) has recently been conceived as a new minimally invasive ablation method, using microsecond electric fields to produce nanoscale defects in the cell membrane bilayer and induce cell death while keeping all other molecules, including the extracellular matrix, intact.
Phillips, MA, Narayan, R, Padath, T, Rubinsky, B   +3 more
openaire   +4 more sources

Irreversible electroporation in pancreatic cancer [PDF]

, 2018
Pancreatic cancer is the deadliest of the gastrointestinal tract with 5-year survival rates of less than 5%. Given common asymptomatic early disease course, most patients (50%) present with an already metastatic disease, while only 20% can undergo ...
Mathias Worni, Gloor, Beat, Holzgang, Melanie, Suna Erdem, Melanie Holzgang, Holzgang, Melanie Martina, Benjamin Eigl, Erdem, Suna, Beat Gloor, Worni, Mathias, Eigl, Benjamin   +10 more
core   +2 more sources

The Influence of Irreversible Electroporation Parameters on the Size of the Ablation Zone and Thermal Effects: A Systematic Review

Technology in Cancer Research & Treatment, 2023
Introduction: The aim of this study was to review the effect of irreversible electroporation parameter settings on the size of the ablation zone and the occurrence of thermal effects.
Annemiek M Hogenes MSc, Christiaan G Overduin PhD, Cornelis H Slump PhD, Cornelis J H M van Laarhoven MD, PhD, Jurgen J Fütterer MD, PhD, Richard P G ten Broek MD, PhD, Martijn W J Stommel MD, PhD   +6 more
doaj   +1 more source

Dynamic Operations in Macromolecular Data Storage

Angewandte Chemie, EarlyView.
With the exponential growth of digital data and the limitations of conventional silicon‐based storage and computing technologies, macromolecular data storage, the practice of encoding digital information within large, complex molecules like DNA or synthetic polymers, has emerged as a scalable and sustainable alternative to traditional digital ...
Jakub Ossowski, Oskar Affenberger, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +2 more sources

Electric field effects of pulsed field ablation through adjacent non-cardiac tissues in an in vitro hybrid model

Frontiers in Cardiovascular Medicine
BackgroundEndocardial ablation of atrial arrhythmias may occasionally produce insufficient lesion depth. Pulsed-field ablation (PFA) may generate measurable electroporation effects beyond interposed non-cardiac tissues, but field propagation across such ...
Denis Fedorov, Laura Dippel, Jan Minners, Johannes Steinfurt, Julian Mueller, Dirk Westermann, Heiko Lehrmann, Thomas Arentz, Martin Eichenlaub   +8 more
doaj   +1 more source

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Preliminary study of steep pulse irreversible electroporation technology in human large cell lung cancer cell lines L9981 [PDF]

Archives of Biological Sciences, 2013
Our aim was to validate the effectiveness of steep pulse irreversible electroporation technology in human large cell lung cancer cells and to screen the optimal treatment of parameters for human large cell lung cancer cells.
Song Zuoqing, Pan Zhenhua, Xu Xiaohong, Wang Weiqiang, Zu Lingling, Wang Jing, Song Zhitao, Liu Hongyu, Li Zhigang, Li Chengxiang, Chen Jun, Yao Chenguo, Zhou Qinghua   +12 more
doaj   +1 more source

An update on irreversible electroporation of liver tumours [PDF]

Hong Kong Medical Journal, 2014
OBJECTIVE. To investigate the clinical efficacy and safety of irreversible electroporation for ablation of liver tumour in humans. DATA SOURCES. The PubMed and MEDLINE databases were systematically searched. STUDY SELECTION. Clinical research published in English in the last 10 years until October 2013 that address clinical issues related to ...
Wong, K, Yeung, ESL, So, ECT, Chan, ACY, Wong, CYK, Chung, MWY   +5 more
openaire   +4 more sources