Results 41 to 50 of about 195,259 (227)

Comparison between high-frequency irreversible electroporation and irreversible electroporation ablation of small swine liver: follow-up of DCE-MRI and pathological observations

Chinese Medical Journal, 2021
. Background:. High-frequency irreversible electroporation (H-FIRE) is a novel, next-generation nanoknife technology with the advantage of relieving irreversible electroporation (IRE)-induced muscle contractions. However, the difference between IRE and H-
Jing Li, Xiao-Bo Zhang, Jing-Jing Wang, Lu-Jia Jin, Hu-Sheng Shan, Xiao Zhang, Li Ma, Xiao-Dong Xue, Xin Zhang, Zhong-Liang Zhang, Liang-Liang Meng, Fei Yuan, Yue-Yong Xiao, Pei-Fang Wei   +13 more
doaj   +1 more source

The First Study of Irreversible Electroporation with Calcium Ions and Chemotherapy in Patients with Locally Advanced Pancreatic Adenocarcinoma

Applied Sciences, 2020
(1) Background: In the last two decades, anticancer treatment has been extensively developed based on various physical methods, including electroporation (EP).
Julia Rudno-Rudzińska, Wojciech Kielan, Maciej Guziński, Maciej Płochocki, Julita Kulbacka   +4 more
doaj   +1 more source

Physiological and histopathological effects of electroporation pulse on stomach of rats

BMC Gastroenterology, 2021
Background Irreversible electroporation (IRE) is an emerging tissue ablation technique with widespread potential, especially for cancer treatment. Although the safety and efficacy of IRE for gastric tissue ablation have been demonstrated, there is a gap ...
Yuchi Zhang, Xuan Han, Zhuoqun Li, Yu Zhang, Lihong Liang, Xiaoying Ma, Haonan Liu, Yihui Gao, Qingshan Li, Xue Chen, Yi Lv, Fenggang Ren   +11 more
doaj   +1 more source

Irreversible Electroporation of Pancreatic Tumors

, 2017
Over 95% of pancreatic cancers are exocrine tumors that bare a dismal prognosis. Although oncological outcome is best for patients presenting with nonmetastatic resectable disease, cure is rarely achieved [1]. Up to 40% of patients present with nonmetastatic disease that is considered unresectable due to vascular encasement (locally advanced pancreatic
Meijerink, Martijn R., Nilsson, Anders, Narayanan, Govindarajan, Martin, Robert   +3 more
openaire   +4 more sources

The Influence of Irreversible Electroporation Parameters on the Size of the Ablation Zone and Thermal Effects: A Systematic Review

Technology in Cancer Research & Treatment, 2023
Introduction: The aim of this study was to review the effect of irreversible electroporation parameter settings on the size of the ablation zone and the occurrence of thermal effects.
Annemiek M Hogenes MSc, Christiaan G Overduin PhD, Cornelis H Slump PhD, Cornelis J H M van Laarhoven MD, PhD, Jurgen J Fütterer MD, PhD, Richard P G ten Broek MD, PhD, Martijn W J Stommel MD, PhD   +6 more
doaj   +1 more source

Irreversible electroporation on the small intestine [PDF]

British Journal of Cancer, 2012
Non-thermal irreversible electroporation (NTIRE) has recently been conceived as a new minimally invasive ablation method, using microsecond electric fields to produce nanoscale defects in the cell membrane bilayer and induce cell death while keeping all other molecules, including the extracellular matrix, intact.
Phillips, MA, Narayan, R, Padath, T, Rubinsky, B   +3 more
openaire   +4 more sources

Clinical course following irreversible electroporation (IRE).

, 2016
Clinical course following irreversible electroporation (IRE).
Jianhua Zhang (6347), Wenlong Zhang (283123), Wei Chai (403946), Kecheng Xu (3373754), Jiuping Wu (3373748), Xulong Zhou (3373757), Xiaomei Luo (502040), Jian Shi (141852), Jianying Zeng (3373751), Lizhi Niu (3373745), Xianjun Liang (3373760), Jiannan Li (1505440), Shuai Guo (1353816), Gang Fang (11785)   +13 more
core   +1 more source

Electric field effects of pulsed field ablation through adjacent non-cardiac tissues in an in vitro hybrid model

Frontiers in Cardiovascular Medicine
BackgroundEndocardial ablation of atrial arrhythmias may occasionally produce insufficient lesion depth. Pulsed-field ablation (PFA) may generate measurable electroporation effects beyond interposed non-cardiac tissues, but field propagation across such ...
Denis Fedorov, Laura Dippel, Jan Minners, Johannes Steinfurt, Julian Mueller, Dirk Westermann, Heiko Lehrmann, Thomas Arentz, Martin Eichenlaub   +8 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source