Results 51 to 60 of about 182,783 (241)

Irreversible electroporation and electrochemotherapy in oncology: State of the art

open access: yes, 2022
International audienceThermal tumor ablation techniques including radiofrequency, microwave, LASER, high-intensity focused ultrasound and cryoablation are routinely used to treated liver, kidney, bone, or lung tumors.
Rols, Marie-Pierre   +2 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Irreversible Electroporation Plus Anti-PD-1 Antibody versus Irreversible Electroporation Alone for Patients with Locally Advanced Pancreatic Cancer

open access: yesJournal of Inflammation Research, 2021
Chaobin He,1,* Shuxin Sun,2,* Yu Zhang,3,* Shengping Li1 1Department of Pancreatobiliary Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center ...
He C, Sun S, Zhang Y, Li S
doaj  

Irreversible Electroporation of Liver Tumors

open access: yes, 2017
The liver is a well-known site for tumors of benign as well as malignant origin. In the Western world, the most frequent hepatic malignancies encountered are liver metastases, especially but not solely from colorectal origin. Primary liver tumors, or the hepatocellular carcinoma (HCC), more frequently develop in people from Asian and Mediterranean ...
Nielsen, Karin   +3 more
openaire   +2 more sources

Dynamic Electroporation Modelling [PDF]

open access: yes, 2009
In this thesis, modelling and simulation of the effects of electric fields on a single spherical cell are undertaken. Of interest is the effect that different electric field waveforms have on the induced transmembrane potential of the cell and by ...
Talele, Sadhana
core  

The Effect of Irreversible Electroporation on Blood Vessels [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2007
We present a pilot study on the long term effects of irreversible electroporation (IRE) on a large blood vessel. The study was motivated by the anticipated use of IRE for treatment of cancer tumors abutting large blood vessels. A sequence of 10 direct current IRE pulses of 3800 V/cm, 100μs each, at a frequency of 10 pulses per second, were applied ...
Elad, Maor   +3 more
openaire   +2 more sources

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

open access: yesAdvanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu   +6 more
wiley   +1 more source

A statistical model describing combined irreversible electroporation and electroporation-induced blood-brain barrier disruption

open access: yesRadiology and Oncology, 2016
Electroporation-based therapies such as electrochemotherapy (ECT) and irreversible electroporation (IRE) are emerging as promising tools for treatment of tumors.
Sharabi Shirley   +7 more
doaj   +1 more source

The effects of irreversible electroporation (IRE) on nerves. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: If a critical nerve is circumferentially involved with tumor, radical surgery intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to serious consequences. In spite of the impressive technical advancements in
Wei Li   +4 more
doaj   +1 more source

Irreversible Electroporation: Implications for Prostate Ablation [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2007
Percutaneous prostate cryo-ablation has become an accepted treatment for primary prostate cancer. Thermal tissue ablation based on cold, however, does have some distinct limitations. These include, variable damage at the cryo lesions margin, injury to adjacent structures such as rectum, urethra and NVB (neurovascular bundle), and long procedure time ...
Gary, Onik, Paul, Mikus, Boris, Rubinsky
openaire   +2 more sources

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