Results 71 to 80 of about 10,834 (232)

Investigation of safety for electrochemotherapy and irreversible electroporation ablation therapies in patients with cardiac pacemakers

open access: yesBioMedical Engineering OnLine, 2020
Background The effectiveness of electrochemotherapy of tumors (ECT) and of irreversible electroporation ablation (IRE) depends on different mechanisms and delivery protocols.
Tomaz Jarm   +5 more
doaj   +1 more source

Rat liver regeneration following ablation with irreversible electroporation [PDF]

open access: yesPeerJ, 2016
During the past decade, irreversible electroporation (IRE) ablation has emerged as a promising tool for the treatment of multiple diseases including hepatic cancer.
Alexander Golberg   +4 more
doaj   +2 more sources

Electroporation in Clinical Applications—The Potential of Gene Electrotransfer and Electrochemotherapy

open access: yesApplied Sciences, 2022
Electroporation (EP) allows for the transport of molecules into the cytoplasm with significant effectiveness by forming transient pores in the cell membrane using electric pulses. This can be used for cellular transport (RE—reversible electroporation) or
Katarzyna Rakoczy   +9 more
doaj   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

The Effect of Irreversible Electroporation on Blood Vessels [PDF]

open access: yesTechnology in Cancer Research & Treatment, 2007
We present a pilot study on the long term effects of irreversible electroporation (IRE) on a large blood vessel. The study was motivated by the anticipated use of IRE for treatment of cancer tumors abutting large blood vessels. A sequence of 10 direct current IRE pulses of 3800 V/cm, 100μs each, at a frequency of 10 pulses per second, were applied ...
Elad, Maor   +3 more
openaire   +2 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

open access: yesAdvanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård   +19 more
wiley   +1 more source

Preparação de um arranjo experimental para a eletroporação de célula única [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013.Este trabalho objetiva a preparação de um arranjo experimental para o estudo da eletroporação de ...
Chiea, Rafael Attili
core  

Irreversible Electroporation as a Bridge to Liver Transplantation [PDF]

open access: yesThe American Surgeon™, 2019
Hepatocellular carcinoma (HCC) in proximity to major hepatic vasculature poses a risk for invasion, which would contraindicate liver transplantation, yet, is difficult to treat with thermal ablation. This study was undertaken to evaluate the feasibility of irreversible electroporation (IRE) as a bridge to transplantation for high-risk tumors.
Robert M, Cannon   +2 more
openaire   +2 more sources

Improving Prediction of the Potential Distribution Induced by Cylindrical Electrodes within a Homogeneous Rectangular Grid during Irreversible Electroporation

open access: yesApplied Sciences, 2022
Background: Irreversible electroporation (IRE) is an ablation technique based on the application of short, high-voltage pulses between needle electrodes (diameter: ~1.0 × 10−3 m). A Finite Difference-based software simulating IRE treatment generally uses
Pierre Agnass   +5 more
doaj   +1 more source

Chapter Irreversible electroporation in pancreatic cancer [PDF]

open access: yes, 2018
Pancreatic cancer is the deadliest of the gastrointestinal tract with 5-year survival rates of less than 5%. Given common asymptomatic early disease course, most patients (50%) present with an already metastatic disease, while only 20% can undergo ...
Gloor, Beat   +4 more
core   +1 more source

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