Results 61 to 70 of about 20,608 (192)

A micro cell lysis device [PDF]

, 1998
A new micromachined cell lysis device is developed. It is designed for miniature bio-analysis systems where cell lysing is needed to obtain intracellular materials for further analysis such as DNA identification.
Lee, S. W., Tai, Y. C., Yowanto, H.
core  

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Investigation of safety for electrochemotherapy and irreversible electroporation ablation therapies in patients with cardiac pacemakers

BioMedical Engineering OnLine, 2020
Background The effectiveness of electrochemotherapy of tumors (ECT) and of irreversible electroporation ablation (IRE) depends on different mechanisms and delivery protocols.
Tomaz Jarm, Tadej Krmac, Ratko Magjarevic, Bor Kos, Helena Cindric, Damijan Miklavcic   +5 more
doaj   +1 more source

Immunologic response to tumor ablation with irreversible electroporation. [PDF]

PLoS ONE, 2012
BACKGROUND: Irreversible electroporation (IRE) is a promising technique for the focal treatment of pathologic tissues, which involves placing minimally invasive electrodes within the targeted region.
Xiaoxiang Li, Kui Xu, Wei Li, Xiuchun Qiu, Baoan Ma, Qingyu Fan, Zhao Li   +6 more
doaj   +1 more source

Electroporation in Clinical Applications—The Potential of Gene Electrotransfer and Electrochemotherapy

Applied Sciences, 2022
Electroporation (EP) allows for the transport of molecules into the cytoplasm with significant effectiveness by forming transient pores in the cell membrane using electric pulses. This can be used for cellular transport (RE—reversible electroporation) or
Katarzyna Rakoczy, Monika Kisielewska, Mikołaj Sędzik, Laura Jonderko, Julia Celińska, Natalia Sauer, Wojciech Szlasa, Jolanta Saczko, Vitalij Novickij, Julita Kulbacka   +9 more
doaj   +1 more source

A toy model of fractal glioma development under RF electric field treatment

, 2012
A toy model for glioma treatment by a radio frequency electric field is suggested. This low-intensity, intermediate-frequency alternating electric field is known as the tumor-treating-field (TTF). In the framework of this model the efficiency of this TTF
A. Chauviere, A. Giese, A. Giese, A. Iomin, A. Iomin, A. Iomin, A. Iomin, A.V. Kolobov, B. Rubinsky, D.H. Geho, E. Baskin, E. Baskin, E. Baskin, E. Khain, E.D. Kirson, E.D. Kirson, G.H. Weiss, H. Hatzikirou, I.M. Sokolov, J.R. Liang, M.I. Stockman, M.V. Berry, R. Metzler, S. Fedotov, S. Fedotov, S. Fedotov, U.A. Khan, V.E. Arkhincheev, Y. Palti, Yu. Polevaya   +29 more
core   +1 more source

Observations on the water distribution and extractable sugar content in carrot slices after pulsed electric field treatment [PDF]

, 2014
peer-reviewedThe impact of pulsed electric field (PEF) processing conditions on the distribution of water in carrot tissue and extractability of soluble sugars from carrot slices was studied.
Aguilo-Aguayo, Ingrid, Brunton, Nigel, Downey, Gerard, Keenan, Derek F., Lyng, James G., Rai, Dilip K.   +5 more
core   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

The effects of irreversible electroporation (IRE) on nerves. [PDF]

PLoS ONE, 2011
BACKGROUND: If a critical nerve is circumferentially involved with tumor, radical surgery intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to serious consequences. In spite of the impressive technical advancements in
Wei Li, Qingyu Fan, Zhenwei Ji, Xiuchun Qiu, Zhao Li   +4 more
doaj   +1 more source

Study of electric field an magnetic field affected biological cells [PDF]

, 2014
This paper presents the elaboration on effect of electric field and magnetic field to biological cells. Electroporation has become important parameter in treatment cancer or tumour cells.
Abdul Manaf, Mohamed Shukri, Abdul Rahim, Ruzairi, Mansor, Mohd. Saiful Badri, Zakaria, Zulkarnay, Zawahir, Mohd. Zikrillah   +4 more
core   +1 more source