Results 91 to 100 of about 195,259 (227)

Irreversible Electroporation in Clinical Practice

, 2018
This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) - better known by its commercial name, NanoKnife - which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early ...
Meijerink, Martijn R., Scheffer, Hester J., Naranayan, Govindarajan   +2 more
openaire   +2 more sources

A numerical investigation of the electric and thermal cell kill distributions in electroporation-based therapies in tissue.

PLoS ONE, 2014
Electroporation-based therapies are powerful biotechnological tools for enhancing the delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs).
Paulo A Garcia, Rafael V Davalos, Damijan Miklavcic   +2 more
doaj   +1 more source

Intraoperative adverse events during irreversible electroporation-a call for caution

, 2016
BACKGROUND Irreversible electroporation is increasingly used for treatment of solid tumors, but safety data remain scarce. This study aimed to describe intraoperative adverse events associated with irreversible electroporation in patients undergoing ...
Glenck, Michael, Clavien, Pierre-Alain, Pfammatter, Thomas, DeOliveira, Michelle L, Castrezana López, Liliana, Bonvini, John M, Kambakamba, Patryk, DeOliveira ML, Glenck M, Clavien PA, Pfammatter T, Bonvini JM, Castrezana López L, Kambakamba P   +13 more
core   +1 more source

Human Embryonic Stem Cell‐Derived Immunity‐And‐Matrix‐Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1‐Mediated Collagen Degradation

Cell Proliferation, EarlyView.
Human embryonic stem cell‐derived Immunity‐and‐Matrix‐Regulatory Cells (IMRCs) effectively attenuate pulmonary fibrosis by secreting Matrix Metalloproteinase‐1 (MMP1), which directly degrades excess collagen I in the extracellular matrix. By directly degrading collagen I, IMRCs reverse ECM stiffness, suppress myofibroblast activation, and promote a ...
Zhongwen Li, Dingyun Song, Faguo Sun, Licheng Song, Bin An, Tingting Gao, Jingjing Liu, Kan Zhang, Kaidi Liu, Kaiwei Wu, Yajing Li, Yi Yang, Yaru Liu, Ruofan Su, Zai Wang, Tiemei Zhao, Huaiyong Chen, Li Xiao, Liang Peng, Liu Wang, Wei Li, Lixin Xie, Jie Hao, Huaping Dai, Jun Wu   +24 more
wiley   +1 more source

Irreversible electroporation for unresectable liver malignancies

Academia Oncology
Background: Irreversible electroporation (IRE) is a non-thermal ablation technique used for liver tumors that are unresectable due to their proximity to critical structures. This study evaluates outcomes for patients treated with IRE. Methods:
Zili Zhou, Chris Wall, Jeff Bird, Shahid Ahmed, Gavin Beck, John Shaw, Michael A. J. Moser   +6 more
doaj   +1 more source

Irreversible electroporation of hepatocellular carcinoma: patient selection and perspectives

, 2017
Asha Zimmerman,1 David Grand,2 Kevin P Charpentier1 1Department of Surgery, 2Department of Radiology, Rhode Island Hospital, Brown University, Providence, RI, USA Abstract: Irreversible electroporation (IRE) is a novel form of tissue ablation that uses ...
Charpentier KP, Zimmerman A, Grand D
core  

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Electroporation phenomena and progress on treatment of advanced progressive pancreatic cancer with irreversible electroporation

肿瘤影像学, 2018
Electroporation or electrical breakdown phenomenon is observed in the plasma membranes where the membrane potential exceeds the critical value, which mechanically induces membrane oscillation, or temporary or permanent nanoscale pore formation that is ...
SHI Qiusheng, DU Lianfang, ZHANG Yanfeng
doaj  

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

The FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong, Mateo P. Hoare, Laura J. Grundy, Filomena Gallo, Karin H. Müller, Ewan St. John Smith, Janet R. Kumita   +6 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source