Results 91 to 100 of about 182,783 (241)

Irreversible Electroporation in Clinical Practice

, 2018
This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) - better known by its commercial name, NanoKnife - which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early ...
Meijerink, Martijn R., Scheffer, Hester J., Naranayan, Govindarajan   +2 more
openaire   +2 more sources

Histopathological Outcomes after Irreversible Electroporation for Prostate Cancer: Results of an Ablate and Resect Study

, 2016
Irreversible electroporation is a tissue ablation modality that uses high voltage electric energy to induce an increase in cell membrane permeability. This causes destabilization of the existing cellular transmembrane potential leading to cell death, due
Zondervan, P. J., Jurhill, R. R., Varkarakis, I. M., de Bruin, D. M., Muller, B. G., Skolarikos, A., de la Rosette, J. J. M. C. H., Postema, A. W., Wagstaff, P. G. K., Laguna Pes, M. P., Savci-Heijink, C. D., van den Bos, W., de Reijke, T. M.   +12 more
core   +3 more sources

Irreversible electroporation for unresectable liver malignancies

Academia Oncology
Background: Irreversible electroporation (IRE) is a non-thermal ablation technique used for liver tumors that are unresectable due to their proximity to critical structures. This study evaluates outcomes for patients treated with IRE. Methods:
Zili Zhou, Chris Wall, Jeff Bird, Shahid Ahmed, Gavin Beck, John Shaw, Michael A. J. Moser   +6 more
doaj   +1 more source

Irreversible electroporation of hepatocellular carcinoma: patient selection and perspectives

, 2017
Asha Zimmerman,1 David Grand,2 Kevin P Charpentier1 1Department of Surgery, 2Department of Radiology, Rhode Island Hospital, Brown University, Providence, RI, USA Abstract: Irreversible electroporation (IRE) is a novel form of tissue ablation that uses ...
Charpentier KP, Zimmerman A, Grand D
core  

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

How We Simulate Nanopores

Small Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz, Xavier Mleziva, Meng Xu, Melika Shekari, Christopher Maffeo, Aleksei Aksimentiev   +5 more
wiley   +1 more source

3D planning of irreversible electroporation treatment in pancreatic carcinoma: a use case [PDF]

, 2018
Irreversible-electroporation (IRE) is an ablation technique that spares vessels and is therefore suitable for treatment of locally advanced pancreatic cancer.
Candinas, Daniel, Gloor, Beat, Peterhans, Matthias, Weber, Stefan, Worni, Mathias, Eigl, Benjamin Peter   +5 more
core   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Careful treatment planning enables safe ablation of liver tumors adjacent to major blood vessels by percutaneous irreversible electroporation (IRE)

Radiology and Oncology, 2015
Background. Irreversible electroporation (IRE) is a tissue ablation method, which relies on the phenomenon of electroporation. When cells are exposed to a sufficiently electric field, the plasma membrane is disrupted and cells undergo an apoptotic or ...
Kos Bor, Voigt Peter, Miklavcic Damijan, Moche Michael   +3 more
doaj   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source