Results 101 to 110 of about 10,834 (232)

Irreversible Electroporation in Clinical Practice

, 2018
This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) - better known by its commercial name, NanoKnife - which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early ...
Meijerink, Martijn R., Scheffer, Hester J., Naranayan, Govindarajan   +2 more
openaire   +2 more sources

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Complications of Percutaneous Irreversible Electroporation for Pancreatic Cancer: A Systematic Review

Journal of Clinical Interventional Radiology ISVIR
Purpose The aim of the study was to systematically review the percutaneous irreversible electroporation (IRE) complications for pancreatic ductal adenocarcinoma (PDAC).
Harsimran Bhatia, Muniraju Maralakunte, Mudita Gulati, Vishal Sharma, Pankaj Gupta   +4 more
doaj   +1 more source

Irreversible electroporation for colorectal cancer liver metastasis: a review

, 2022
Irreversible electroporation (IRE) ablation is gaining popularity over the last decade as a nonthermal alternative to thermal ablation technologies such as radiofrequency ablation (RFA) and Microwave ablation (MWA).
Nicole Wilson, Yilun Koethe, Govindarajan Narayanan   +2 more
core   +1 more source

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

BJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam, Bishoy Hanna, Stuart Jackson, Stephen McCombie, George McClintock, Matthew J. Roberts, Jake Rahkala, Jeremy Teoh, Mohan Arianayagam, Bertram Canagasingham, Ahmed Saeed Goolam, Nicola Jeffery, Matthew Winter, Mohamed Khadra, Raymond Ko, Nicholas Mehan, Isaac Thangasamy, Celi Varol   +17 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

IRREVERSIBLE ELECTROPORATION OF COLORECTAL LIVER METASTASES WITH THE "NANOKNIFE" SYSTEM

, 2013
Due to recent advances in minimally invasive surgery, there is a new ablation technique – the irre-versible electroporation (IRE), based on the effect of electric fields.
Yu Viktorovich Ivanov, A Aleksandrovich Nechunaev, F Georgievich Zabozlaev, D Yur'evich Pikunov, D Nikolaevich Panchenkov, M Petrovna Kochieva, G Babkenovna Aleksanyan   +6 more
core   +1 more source

Palliative treatment of presacral recurrence of endometrial cancer using irreversible electroporation: a case report [PDF]

, 2013
INTRODUCTION: Irreversible electroporation (IRE) is a new minimally invasive tumor ablation technique which induces irreversible disruption of cell membrane integrity by changing the transmembrane potential resulting in cell death.
Niessen, Christoph, Michael Rechenmacher, Jung, Ernst-Michael, Joachim Hahn, Christoph Niessen, Rechenmacher, Michael, Ernst-Michael Jung, Wohlgemuth, Walter A., Philipp Wiggermann, Walter A Wohlgemuth, Trabold, Benedikt, Wiggermann, Philipp, Christian Stroszczynski, Schreyer, Andreas G., Hahn, Joachim, Stroszczynski, Christian, Andreas G Schreyer, Benedikt Trabold   +17 more
core   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

A characterization of the reversibly electroporated penumbra during irreversible electroporation

Cancer Treatment and Research Communications
Irreversible electroporation (IRE) is a novel anticancer ablative treatment, which has been proposed to enhance the efficacy of chemotherapy in the periphery of the ablated area by capturing chemotherapy intracellularly. The aim of the current trial was to characterize the ablated lesion to get spatial information about the distribution of captured ...
Rasmus Virenfeldt Flak, Jonatan Riber Granborg, Christian Janfelt, Martin Skovmos Nielsen, Benedict Kjærgaard, Ole Thorlacius-Ussing   +5 more
openaire   +3 more sources