Results 171 to 180 of about 900,457 (343)
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Purpose. To study an effect of excimer laser with different wavelengths (248, 308 and 353nm) on sclera.Material and methods. For the experiment 3 laser units, generating radiation with wavelengths of 248, 308 and 353nm were created. There were determined
V. V. Chernykh+6 more
doaj
An Ablation Rate for Lake Fryxell, Victoria Land, Antarctica [PDF]
R. A. Henderson+5 more
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Heating analysis for the Pioneer Venus multiprobe mission [PDF]
The fully coupled, radiating flow field around the entry probes is determined from a detailed calculation which includes equilibrium chemistry, nongray radiative transport, ablation product injection, and a laminar or turbulent boundary layer.
Sutton, K.
core +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
An Approach to Catheter Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter
Much of our understanding of the mechanisms of macro re-entrant atrial tachycardia comes from study of cavotricuspid isthmus (CTI) dependent atrial flutter.
Mark D O’Neill+10 more
doaj
Urinary steroid assays and response to endocrine ablation. [PDF]
B.S. Thomas, R.D. Bulbrook, J.L. Hayward
openalex +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source