Results 71 to 80 of about 873,697 (316)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Near-field simulations of pellet ablation for disruptions mitigation in tokamaks [PDF]

, 2020
Detailed numerical studies of the ablation of a single neon pellet in the plasma disruption mitigation parameter space have been performed. Simulations were carried out using FronTier, a hydrodynamic and low magnetic Reynolds number MHD code with explicit tracking of material interfaces. FronTier's physics models resolve the pellet surface ablation and
arxiv   +1 more source

Cryothermal Energy Ablation Of Cardiac Arrhythmias 2005: State Of The Art [PDF]

, 2005
At the time of antiarrhythmic surgery, cryothermal energy application by a hand-held probe was used to complement dissections and resections and permanently abolish the arrhythmogenic substrate.
De Ponti, Roberto
core   +2 more sources

Impact of open de-ionized water thin film laminar immersion on the liquid immersed ablation threshold and ablation rate of features machined by KrF excimer laser ablation of bisphenol A polycarbonate [PDF]

, 2009
Debris control and surface quality are potential major benefits of sample liquid immersion when laser micromachining; however, the use of an immersion technique potentially modifies the ablation mechanism when compared to an ambient air interaction.
C.F. Dowding, Cooper, Dowding, Dyer, Elaboudi, Elaboudi, Elaboudi, Fabbro, Gray, Hecht, J. Lawrence, Kelly, Lee, Lemoine, Louden, Parvin, Prasad, Xu, Xu, Xu, Yang, Yung, Zangeneh, Zhu   +23 more
core   +2 more sources

Trans‐aortic pulmonary vein isolation using magnetic navigation system for paroxysmal atrial fibrillation in a patient with dextrocardia, situs inversus, and inferior vena cava continuity with azygos vein

Journal of Arrhythmia, 2018
A 51‐year‐old male with dextrocardia and situs inversus underwent catheter ablation for paroxysmal atrial fibrillation. Because the procedure through the trans‐septal approach was impossible due to the inferior vena cava continuity with azygos vein, we ...
Katsunori Okajima, Tomoyuki Nakanishi, Hirotoshi Ichibori, Takeaki Shirai, Makoto Kadotani, Hiroki Shimizu, Yoshio Onishi, Kohei Yamashiro   +7 more
doaj   +1 more source

Macrophage activity at the site of tumor ablation can promote murine urothelial cancer via transforming growth factor-β1

Frontiers in Immunology, 2023
Cell death and injury at the site of tumor ablation attracts macrophages. We sought to understand the status and activity of these cells while focusing on transforming growth factor-β1 (TGF-β1), a potent immunosuppressive and tumorigenic cytokine ...
Yasushi Kimura, Yasushi Kimura, Masashi Fujimori, Neeraj Raghuraman Rajagopalan, Krish Poudel, Kwanghee Kim, Karan Nagar, Laurien GPH. Vroomen, Henning Reis, Hikmat Al-Ahmadie, Jonathan A. Coleman, Govindarajan Srimathveeravalli, Govindarajan Srimathveeravalli   +12 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Ablation article and method [PDF]

, 1973
An ablation article, such as a conical heat shield, having an ablating surface is provided with at least one discrete area of at least one seed material, such as aluminum. When subjected to ablation conditions, the seed material is ablated.
Erickson, W. D., Sullivan, E. M.
core   +1 more source

Ion distribution and ablation depth measurements of a fs-ps laser-irradiated solid tin target [PDF]

, 2017
The ablation of solid tin surfaces by an 800-nanometer-wavelength laser is studied for a pulse length range from 500 fs to 4.5 ps and a fluence range spanning 0.9 to 22 J/cm^2.
A. Antoncecchi, A. S. Stodolna, E. E. B. Leerssen, J. Versluis, K. S. E. Eikema, Krüger J., M. J. Deuzeman, N. Spook, O. O. Versolato, R. Hoekstra, S. Witte, T. Kleijntjens, Vinokhodov A., W. Ubachs   +13 more
core   +3 more sources

Long-term outcomes of radiofrequency ablation for intrathoracic goiter up to 5 years: evaluated by computed tomography/magnetic resonance imaging and ultrasound

International Journal of Hyperthermia
Objectives This study evaluated the long-term efficacy and safety of radiofrequency ablation (RFA) for intrathoracic goiter (ITG) over a follow-up period exceeding six months.Methods From 2017 to 2022, 22 patients (6 males, 16 females) with 24 ITGs ...
Yu-Hsin Wang, Pi-Ling Chiang, An-Ni Lin, Cheng-Kang Wang, Chih-Ying Lee, Chen-Kai Chou, Yen-Hsiang Chang, Shun-Yu Chi, Sheng-Dean Luo, Wei-Che Lin   +9 more
doaj   +1 more source