Results 71 to 80 of about 361,060 (267)

Identification of the Ectopic Foci of Focal Atrial Tachycardia (FAT) by Using Electrocardiogram (ECG) Signal Analysis [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان
Background and Aim: Cardiac electrophysiology study (EPS) is the study of the electrical system of the heart. One of the most common methods of treating cardiac arrhythmias is ablation.
Fatemeh Mohammadi, Ali Sheikhani, Farbod Razzazi, Alireza Ghorbani Sharif   +3 more
doaj  

Comparative Efficacy and Safety of Cryoballoon vs Laser Balloon Ablation for Pulmonary Vein Isolation in Patients With Paroxysmal Atrial Fibrillation

Journal of Patient-Centered Research and Reviews
Purpose: Atrial fibrillation (AF), the most common arrhythmia in older adults, is often treated with cryoballoon ablation (CBA) or laser balloon ablation (LBA) when refractory to medication.
Mahmoud Ali, Dorota Magdon, Abdulghani Mounir, Lynn Erickson, James Adefisoye, Jim Kanani, Andy Kieu, Abdullah Malik, Ali Ali, Nour Ghosoun, Jodi Zilinski, Arshad Jahangir, M. Eyman Mortada, Imran Niazi, Atul Bhatia   +14 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

(Ti,Zr,Hf,Ta)CN/SiCN: A new ultrahigh-temperature ceramic nanocomposite with excellent mechanical properties and ablation resistance

Journal of Advanced Ceramics
Dense monolithic (Ti,Zr,Hf,Ta)CN/SiCN ceramic nanocomposites are prepared via the pyrolysis of novel (Ti-,Zr-,Hf-,Ta)-containing single-source precursors (SSPs) and spark plasma sintering (SPS) with a high heating rate.
Tianxing Jiang, Qingbo Wen, Li Lu, Shasha Tao, Shuibin Wang, Jinrun Hu, Yi Zeng, Xiang Xiong   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Epicardial Electrical Activation During Atrial Fibrillation

JACC: Case Reports, 2019
High-definition mapping of atrial fibrillation is most commonly performed from the endocardial surface. This report describes an example of a case in which combined mapping of the endocardium and epicardium of the left atrium demonstrated electrical ...
Kathryn L. Hong, BSc, MSc, Jason Baley, BSc, Adrian Baranchuk, MD, Gianluigi Bisleri, MD, Benedict M. Glover, MD   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source