BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Mechanical bowel displacement to enable safe microwave ablation of a peripheral hepatic tumor in Chilaiditi anatomy. [PDF]
Radiol Case RepLiljedahl S, Morcos D, Kitley C.
europepmc +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Combined Ultrasound- and Fluoroscopy-guided Percutaneous Cementoplasty and Ablation for a C2 Pathologic Fracture: A Case Report. [PDF]
J Orthop Case RepKim J +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Bronchoscopic Ablation and Intratumoral Therapies for Lung Cancer: Expanding Local Treatment Beyond Surgical Resection. [PDF]
Cancers (Basel)Parton T +4 more
europepmc +1 more source
Endoscopic ultrasonography ablation for small pancreatic neuroendocrine tumors. [PDF]
J Gastrointest OncolSrinivasan T, Gonda T.
europepmc +1 more source
Single versus double transseptal puncture for atrial fibrillation radiofrequency ablation: a systematic review and meta-analysis. [PDF]
Front Cardiovasc MedXu J +5 more
europepmc +1 more source