Results 61 to 70 of about 134,028 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Complications after thermal ablation for thyroid nodules across countries

Frontiers in Endocrinology
ObjectiveThermal ablation is an effective treatment for thyroid nodules; however, the range of complications associated with thermal ablation is unclear.
Shuang Wu, Yantao Cai, Xiaoyu Liu, Chenfang Zhu   +3 more
doaj   +1 more source

Impact of an immediate short waiting period on ultrasound-based ablative margin assessment following radiofrequency ablation for hepatocellular carcinoma [PDF]

Ultrasonography
Purpose This study aimed to evaluate whether an immediate short waiting period after radiofrequency ablation (RFA) can improve the accuracy of ultrasound (US)-based assessment of the ablation zone in patients with hepatocellular carcinoma (HCC).
Seungchul Han, Min Woo Lee, Kyowon Gu, Hyunchul Rhim   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quantitative analysis of lung microwave ablation zone volume and shape

European Radiology Experimental
Objective We quantified volume and shape variability in lung microwave ablation (LMWA) zones, comparing them with expected ablation zones, exploring the correlation with tissue contraction. Materials and methods After Institutional Review Board approval,
Robert S. Salkin, Arvind B. Dev, Erica S. Alexander, Amgad Moussa, Vlasios Sotirchos, Constantinos T. Sofocleous, Gilbert Maroun, Eslam W. Youssef, Mario Ghosn, E. Nadia Petre, Stephen B. Solomon, Krishna Nand Keshavamurthy, Etay Ziv   +12 more
doaj   +1 more source

Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy in a patient with prior transcatheter aortic valve replacement

Cardiology Plus, 2020
A 68-year-old man presented with chest distress recurring for the past 10 years. An echocardiogram demonstrated bicuspid aortic valve malformation with severe aortic stenosis and ventricular septal thickness of 22 mm.
Jian-An Wang, Xin-Ping Lin, Ju-Bo Jiang, Xian-Bao Liu, Jun Jiang, Zhao-Xia Pu, Li-Han Wang, Hua-Jun Li, Fei Lv   +8 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Pulsed field ablation for atrial fibrillation: a comprehensive bibliometric analysis of research trends and emerging Frontiers

Frontiers in Cardiovascular Medicine
BackgroundAtrial fibrillation (AF) is the most prevalent cardiac arrhythmia worldwide, posing significant health burdens. Pulsed field ablation (PFA) is an emerging non-thermal technique that is gaining traction due to the ability to selectively target ...
Li Li, Bin Xie
doaj   +1 more source

Radiofrequency Ablation of Hepatocellular Carcinoma (≤ 5 cm) with Saline-Perfused Electrodes: Factors Affecting Local Tumor Progression

대한영상의학회지, 2020
Purpose We aimed to assess local tumor progression (LTP) rate and associated prognostic factors in 92 patients who underwent radiofrequency ablation (RFA) using saline-perfused electrodes to treat hepatocellular carcinoma (HCC) (≤ 5 cm). Materials and
Dong Ho Kim, Dong Jin Chung, Se Hyun Cho, Joon-Yeol Han   +3 more
doaj   +1 more source