Results 131 to 140 of about 125,321 (287)

Modified Kestenbaum surgery for correction of abnormal head posture in infantile nystagmus: outcome in 63 patients with graded augmentaton

open access: yes, 2000
PURPOSE: To analyze the surgical effect of modified Kestenbaum surgery and show how to determine the amount of appropriate augmentation for correction of abnormal head posture in infantile nystagmus.
이종복
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Analysis of factors affecting the surgical efficacy for elderly intertrochanteric fracture

open access: yesFrontiers in Surgery
ObjectiveTo explore the relevant factors affecting the efficacy of surgery for intertrochanteric fracture.MethodsA retrospective case series study was conducted to analyze the clinical data of 212 patients with intertrochanteric fractures from January ...
Xiang Yu   +4 more
doaj   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Determining Knee Loading for Abnormal Gait

open access: yes, 2014
The purpose of this study was to take known experimental loads throughout normal gait and to find the corresponding loading at the knee for both normal gait and abnormal gait. Abnormal gait was defined as a person with varus, i.e.
Norman, Timothy L.   +3 more
core  

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

open access: yesAdvanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao   +8 more
wiley   +1 more source

Perbedaan Penggunaan Moxa dan Prenatal Yoga terhadap Perubahan Posisi Janin Abnormal

open access: yes
Problems that pregnant women may experience are abnormalities in fetal presentation. Therapy is needed to increase fetal activity so that it is hoped that the fetus can rotate from breech presentation to head presentation.
Friscila, Ika   +3 more
core   +1 more source

Car Driver Position Detection System

open access: yes, 2020
Diplomová práce je zaměřena na řešení snímání polohy řidiče k možnému využití jako asistenční služby do vozidla. Zabývá se různými možnostmi snímání polohy řidiče za pomocí kamerového systému.
Miesbauer, Petr
core  

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