Results 261 to 270 of about 450,317 (308)
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Drug-Induced Nail Abnormalities
American Journal of Clinical Dermatology, 2003This article reviews the different nail symptoms produced by drugs. Drug-induced nail abnormalities may result from toxicity to the matrix, the nail bed or the periungual tissues. The most common symptoms include Beau's lines/onychomadesis, melanonychia, onycholysis, and periungual pyogenic granulomas.
Piraccini, Bianca Maria +2 more
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Idiosyncratic Drug-Induced Haematological Abnormalities
Drug Safety, 1994Haematological dyscrasias remain important because they are potentially fatal. Their accurate reporting is required to confirm the cause-effect relationship of suspected adverse drug reactions (ADRs); to estimate their incidence; and, by risk-benefit analysis of such events, to introduce preventive measures to reduce their impact.
W N, Patton, S B, Duffull
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Drug-induced cardiac abnormalities in premature infants and neonates
American Heart Journal, 2018The Cardiac Safety Research Consortium (CSRC) is a transparent, public-private partnership that was established in 2005 as a Critical Path Program and formalized in 2006 under a Memorandum of Understanding between the United States Food and Drug Administration and Duke University.
Luana, Pesco-Koplowitz +5 more
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DRUG-INDUCED HEPATIC VASCULAR ABNORMALITIES
Clinics in Liver Disease, 1998A wide variety of vascular abnormalities of the liver can occur as a result of drug therapy. The diverse morphologic lesions produced by medications include sinusoidal dilatation, peliosis hepatis, vasculitis, hepatic venous outflow obstruction, veno-occlusive disease, hepatoportal sclerosis, angiosarcoma, and nodular regenerative hyperplasia.
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Abnormalities and Drug-Induced Alterations of Vasopressin in Human Hypertension
Clinical Science, 19811. Plasma vasopressin was estimated in 20 normotensive, 46 moderate hypertensive and 14 severe hypertensive patients under normal sodium diet. 2. In moderate hypertensive patients basal values for plasma vasopressin (PVP) after overnight dehydration and 24 h urinary vasopressin (UVP) were respectively 1.82 ± 0.23 pmol/l and 44 ± 4 pmol ...
M, Thibonnier +5 more
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Monitoring Abnormal Laboratory Values as Antecedents to Drug-Induced Injury
The Journal of Trauma: Injury, Infection, and Critical Care, 2005Clinical abnormalities associated with drug therapy may lead to injury if untreated. Detection of preceding drug-related hazardous conditions (DRHCs) may provide the opportunity to prevent injury. This study evaluated the frequency of abnormal laboratory values attributed to the effect of drugs.A total of 590 patients consecutively admitted to a ...
Sandra L, Kane-Gill +3 more
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Lymphocyte abnormality in human myotonic dystrophy and experimental drug‐induced myotonia
Neurology, 1982In the cytoplasm of peripheral blood lymphocytes in 3 of 13 patients with myotonic dystrophy, myelin-like structures were observed electronmicroscopically. Some were connected to the cytoplasmic membranes, and some were surrounded by a limiting membrane possessing acid phosphatase activity.
A, Hiraoka +3 more
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Drug-Induced Abnormalities of Liver Heme Biosynthesis
2020In the liver most of the heme synthesized by the parenchymal cells is apparently destined for the cytochromes of the P450 group, a family of related but distinct hemoproteins under the control of separate genes. Protoporphyrinogen is then oxidized to protoporphyrin by another oxidase and the last enzyme of heme biosynthesis, ferrochelatase, inserts ...
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Aspirin-Sensitive Asthma: Abnormal Platelet Response to Drugs Inducing Asthmatic Attacks
International Archives of Allergy and Immunology, 1985The pathogenesis of aspirin-sensitive asthma remains unknown. Using a new model of platelet activation, initially described as a response of platelets to IgE antibody-dependent stimuli, this study was designed to test the hypothesis of a possible involvement of platelets in aspirin-sensitive asthma. Washed platelets from 35 aspirin-sensitive asthmatics
Jean Claude Ameisen +8 more
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[752] DRUG-INDUCED HEPATITIS IN PATIENTS HOSPITALIZED FOR ABNORMAL LIVER TESTS
Journal of Hepatology, 2007ackgrounds and aims. Adverse drug reactions account far 3–7% of acute ospital admission. An acute hepatic injury due to drugs (DII-been reported o occur in 5–10% of patients hospitalized for jaundice. The aim of study as to analyze the incidence and the outcome c in patients hospitalized far levated serum aminotransferases and/or bilirubin levels ...
C. Prisco +3 more
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