Results 11 to 20 of about 1,171,990 (253)

Genetic Abnormalities in Multiple Myeloma: Prognostic and Therapeutic Implications

Cells, 2021
Some genetic abnormalities of multiple myeloma (MM) detected more than two decades ago remain major prognostic factors. In recent years, the introduction of cutting-edge genomic methodologies has enabled the extensive deciphering of genomic events in MM.
Ignacio J. Cardona-Benavides, Cristina de Ramón, Norma C. Gutiérrez   +2 more
doaj   +1 more source

Una variación anatómica: la desembocadura aberrante del conducto torácico

Biomédica: revista del Instituto Nacional de Salud, 2009
En uno de los cadáveres disecados durante el primer semestre de 2006 en el anfiteatro del Departamento de Morfología de la Universidad del Valle en Cali (Colombia), se encontró una variación anatómica poco descrita en la literatura científica mundial. Se
Elizabeth Peña, Janneth Zuñiga
doaj   +1 more source

Chromosomal aberrations in transitional cell carcinoma that are predictive of disease outcome are independent of polyploidy [PDF]

, 1999
Objective To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects ...
Adie, L., Bartlett, J.M.S., Going, J.J., Grigor, K.M., Watters, A.D.   +4 more
core   +1 more source

Congenital Abnormalities and Multiple Sclerosis

BMC Neurology, 2010
Background There is a strong maternal parent-of-origin effect in determining susceptibility to multiple sclerosis (MS). One hypothesis is that an abnormal intrauterine milieu leading to impaired fetal development could plausibly also result in increased ...
Orton Sarah-Michelle, Dyment David A, Criscuoli Maria, Guimond Colleen, Ramagopalan Sreeram V, Yee Irene M, Ebers George C, Sadovnick Dessa   +7 more
doaj   +1 more source

A longitudinal study of abnormalities on MRI and disability from multiple sclerosis [PDF]

, 2002
Background: In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T2-weighted magnetic resonance imaging (MRI) of ...
Brex, P.A., Ciccarelli, O., Miller, D.H., O'Riordan, J.I., Sailer, M., Thompson, A.J.   +5 more
core   +1 more source

Multiple Congenital Heart Abnormalities

Acta Medica Bulgarica, 2019
Congenital heart abnormalities are rare and most often occur separately. These structural and functional disorders can cause a range of diseases that vary in severity, from mild or even asymptomatic to severe and life-threatening.
Lazarov S., Bogdanov G., Nikolov R.
doaj   +1 more source

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. [PDF]

, 2015
BackgroundAutism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microRNA (miRNA), could have profound ...
Ander, Bradley P, Barger, Nicole, Schumann, Cynthia M, Sharp, Frank R, Stamova, Boryana   +4 more
core   +1 more source

The strong association of left-side heart anomalies with Kabuki syndrome [PDF]

Korean Journal of Pediatrics, 2015
PurposeKabuki syndrome is a multiple congenital malformation syndrome, with characteristic facial features, mental retardation, and skeletal and congenital heart anomalies.
Ja Kyoung Yoon, Kyung Jin Ahn, Bo Sang Kwon, Gi Beom Kim, Eun Jung Bae, Chung Il Noh, Jung Min Ko   +6 more
doaj   +1 more source

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism [PDF]

, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
A Gozzi, A Gozzi, A Gozzi, A Gozzi, A Gozzi, AA Turk, AC Stanfield, AE Dorr, Alberto Galbusera, Alessandro Gozzi, Allan V. Kalueff, Angelo Bifone, AY Hardan, AY Hardan, B Avants, BA Babineau, BB Avants, BB Avants, BB Avants, BU Meye, D Badaruddin, D Wahlsten, D Wahlsten, E Anagnostou, F Tovar-Moll, G Zaharchuk, H Ito, H Utsunomiya, J Ashburner, J Ellegood, JL Silverman, JL Silverman, JL Silverman, JL Whitwell, JM Mountz, JP Lerch, JP Lerch, KL Hyde, L Ferrari, L Ferrari, LK Paul, LK Paul, Luca Dodero, M Magnuson, M Sasaki, M Wohr, M Yang, M Yang, M Yang, M Zilbovicius, MA Just, Maria Luisa Scattoni, Mario Damiano, ME Vissers, ML Scattoni, ML Senjem, MM Haznedar, MM Haznedar, MS George, N Boddaert, N Hadjikhani, O Devinsky, R Adolphs, R Via E, RG Gonzalez, RJ Zatorre, S Mori, S Schobel, S Shen, SM Smith, Sotirios A. Tsaftsaris, SR Das, SS Moy, SS Moy, T Ohnishi, T Ren, TW Frazier, VJ Bolivar, WS Brown   +78 more
core   +3 more sources

The incidence and interrelationship of hemivertebra and concomitant cardiac abnormalities in congenital scoliosis

BMC Musculoskeletal Disorders, 2023
Background Congenital scoliosis(CS) is associated with multiple organs defect, and cardiac abnormalities have been reported commonly associated with CS. Hemivertebra is caused by the failure of vertebral formation, which is a major constitute of CS. Till
Shengru Wang, Yiwei Zhao, You Du, Jianguo Zhang, Bin Yu   +4 more
doaj   +1 more source