Results 1 to 10 of about 61,668 (260)

Chromosomal aberrations as a cause of infertility: diagnosis and genetic counseling in Las Tunas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: infertility is a clinical problem with a significant social medical impact on the health of the couple. It is considered that 36 % of the genetic causes of infertility are caused by chromosomal aberrations.Objective: to describe the results ...
Enelis Reyes Reyes, Nora María Orive Rodríguez, Glenys Katiuska Silva González, Lisset Romero Portelles, Ivette Díaz Plá   +4 more
doaj  

Evaluation of the individual radiosensitivity of a person on the basis of differentiated coloring of chromosomes in peripheral blood lymphocytes

Доповiдi Нацiональної академiї наук України, 2019
A determination and a prediction of the individual radiation sensitivity (IRS) of a person remains an actual problem in the field of radiobiology.
E.A. Domina, J.V.Gontar, L.A. Illyuchok, О.O. Grynchenko   +3 more
doaj   +1 more source

Use of human lymphocyte G0 PCCs to detect intra- and inter-chromosomal aberrations for early radiation biodosimetry and retrospective assessment of radiation-induced effects.

PLoS ONE, 2019
A sensitive biodosimetry tool is required for rapid individualized dose estimation and risk assessment in the case of radiological or nuclear mass casualty scenarios to prioritize exposed humans for immediate medical countermeasures to reduce radiation ...
Terri L Ryan, Antonio G Pantelias, Georgia I Terzoudi, Gabriel E Pantelias, Adayabalam S Balajee   +4 more
doaj   +1 more source

Chromosome-specific aberrations, rather than general aneuploidy, may drive mouse embryonic stem cell-derived teratoma metastasis

Stem Cell Research & Therapy
Introduction Pluripotent stem cells (PSC) are known to recurrently acquire genetic aberrations including chromosomal aneuploidy during long-term culture of which the consequences remain largely unknown.
Joaquin Montilla-Rojo, Sanne Hillenius, Thomas F. Eleveld, Daniela C.F. Salvatori, Leendert H.J. Looijenga   +4 more
doaj   +1 more source

Dynamics of cytogenetic aberrations in Philadelphia chromosome positive and negative hematopoiesis during dasatinib therapy of chronic myeloid leukemia patients after imatinib failure

Haematologica, 2007
Clonal cytogenetic aberrations of the Philadelphia chromosome (Ph) positive hematopoiesis have been associated with the natural evolution of chronic myeloid leukemia (CML) to advanced disease.
Alice Fabarius, Claudia Haferlach, Martin C. Müller, Philipp Erben, Tanja Lahaye, Michelle Giehl, Oliver Frank, Wolfgang Seifarth, Rüdiger Hehlmann, Andreas Hochhaus   +9 more
doaj   +1 more source

Combined use of bacterial artificial chromosomes-on-beads with karyotype detection improves prenatal diagnosis

Molecular Cytogenetics, 2019
Background This study evaluated the individual and combined diagnostic performance of the bacterial artificial chromosomes (BACs)-on-Beads (BoBs™) assay and conventional karyotyping for the prenatal detection of chromosomal abnormalities in pregnant ...
Zhengyou Miao, Xia Liu, Furong Hu, Ming Zhang, Pingli Yang, Luming Wang   +5 more
doaj   +1 more source

Chromosome segregation errors during early embryonic development

Reproductive Medicine and Biology
Background Mitosis maintains a genome's genetic information in daughter cells by accurately segregating chromosomes. However, chromosome aberrations are common during early mammalian embryogenesis.
Hirohisa Kyogoku
doaj   +1 more source

Cytogenetic Analysis of Peripheral Blood Lymphocytes of Workers Occupationally Exposed to Benzene in A Fuel Station in Erbil City- Iraq

Science Journal of University of Zakho, 2016
The objective of the present study was to evaluate genotoxic effects in petrol station workers, who were previously exposed occupationally to benzene in comparison with a selected control group, through inhalation and skin contamination, by using the ...
Hazha J. Hidayat, Mohammed S. Ismael, Hewa H. Hasan   +2 more
doaj  

Chromosome Aberrations as Bioindicators of Environmental Genotoxicity

Biomolecules & Biomedicine, 2007
Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples ...
Slavica Ibrulj, Sanin Haverić, Anja Haverić   +2 more
doaj   +1 more source

Establishing the Link between X-Chromosome Aberrations and TP53 Status, with Breast Cancer Patient Outcomes. [PDF]

Cells, 2023
Caramia F, Speed TP, Shen H, Haupt Y, Haupt S.   +4 more
europepmc   +1 more source