Results 61 to 70 of about 1,601,180 (312)
Introduction: Gemination is the division of a dental follicle that results in a tooth with two crowns, where the number of teeth in the arch does not vary.
Sair Andrés Miquet-Vega +1 more
doaj +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
M. Palmaris longus anomaly was determined in a female patient who applied to our clinic with the compIaints of pain and swelling on the volar surface of the right forearm.
Sitki Percin, Mehmet Cimen
doaj
Normality and abnormality [PDF]
‘Normal’ comes from the latin norma , a carpenter's square, and in mediaeval times meant something at a right angle or perpendicular. A few centuries later it came to mean conforming to a standard and was used in physics to refer to the average of a set of variables.
openaire +2 more sources
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Morphological abnormalities in Tribolium castaneum (Herbst) and Tribolium confusum Duval due to cyromazine and pirimiphos-methyl treatments alone or in combination [PDF]
Newly hatched (24 h old) larvae of Tribolium castaneum and T. confusum were allowed to feed on different doses of cyromazine or pirimiphos-methyl, or on a combined dose of both compounds up to pupation.
AHM Kamaruzzaman +3 more
doaj
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Electrocardiographic Pattern and Cardiovascular Risk Factors among University Students in Dar es salaam – Tanzania [PDF]
Abnormal resting electrocardiogram (ECG) findings have been strongly associated with subsequent increase in all cause CAD and CVD mortality. The abnormalities are defined as either major or minor based on the different criteria.
Kimambo, D.C, Kimambo, Delilah Charles
core

