Results 81 to 90 of about 1,471,166 (317)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

ORAL PARAFUNCTIONAL HABITS AMONG PRESCHOOL CHILDREN IN UKRAINE: A SINGLE-CENTER LONGITUDINAL STUDY

Український стоматологічний альманах
Objective. This study aims to investigate the prevalence of harmful oral habits in children before and after the full-scale invasion of Ukraine, to examine the efficacy of the Froggy Mouth myofunctional rehabilitation approach for atypical swallowing ...
N.P. Makhlynets, D.B. Plishka, M.B. Kokoshko, Z.R. Ozhohan, N.M. Kozan   +4 more
doaj   +1 more source

Slipped capital femoral epiphysis

Journal of the Belgian Society of Radiology, 2014
Background: A 10-year-old boy presented with a 4-week history of limping gait and right knee pain. The patient did not have a fever. Physical examination revealed limited range of motion of the right hip.
L Topff, G Gelin, M Grieten
doaj   +1 more source

Glucose abnormalities in Asian patients with chronic hepatitis C

, 2015
Qingyan Bo,1 Roberto Orsenigo,2 Junyi Wang,1 Louis Griffel,3 Clifford Brass3 1Beijing Novartis Pharma Co. Ltd., Shanghai, People’s Republic of China; 2Novartis Pharma AG, Basel, Switzerland; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ,
Bo Q, Brass C, Orsenigo R, Griffel L, Wang J   +4 more
core  

Association of electrocardiogram abnormalities and incident heart failure events [PDF]

, 2014
BACKGROUND Unless effective preventive strategies are implemented, aging of the population will result in a significant worsening of the heart failure (HF) epidemic.
Applegate, William B, Study, Health ABC, Vittinghoff, Eric, Auer, R., Newman, Anne, Applegate, W.B., Auer, Reto, Kalogeropoulos, Andreas, Vittinghoff, E., Gencer, Baris, Marques-Vidal, Pedro, Marques-Vidal, P., Butler, Javed, Gencer, B., Satterfield, Suzanne, Satterfield, S., Rodondi, Nicolas, Butler, J., Newman, A., Bauer, D.C., Harris, T., Kalogeropoulos, A., Harris, Tamara, Rodondi, N., Bauer, Douglas C   +24 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism

, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
Scattoni, Maria Luisa, Gozzi, Alessandro, Sotirios A Tsaftsaris, Tsaftsaris Sotirios A., Angelo Bifone (232236), Bifone Angelo, Mario Damiano (471358), Scattoni Maria Luisa, Bifone, Angelo, Alberto Galbusera (471359), Maria Luisa Scattoni (270655), Dodero Luca, Luca Dodero (471357), Gozzi Alessandro, Galbusera Alberto, Damiano Mario, Mario Damiano, Alberto Galbusera, Angelo Bifone, Alessandro Gozzi (232210), Tsaftaris, Sotirios A., Damiano, Mario, Galbusera, Alberto, Sotirios A. Tsaftsaris (471360), Luca Dodero, Maria Luisa Scattoni, Dodero, Luca, Alessandro Gozzi, Sforazzini, Francesco   +28 more
core   +1 more source

Paracellin-1 gene mutation with multiple congenital abnormalities [PDF]

, 2006
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is an autosomal recessive renal tubular disorder characterized by renal magnesium wasting, hypercalciuria, advanced nephrocalcinosis and progressive renal failure.
Kavukçu, Salih, Böber, Ece, Konrad, Martin, Türkmen, Mehmet, Kasap, Belde, Soylu, Alper   +5 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source