Results 81 to 90 of about 1,712,683 (311)

Associated Congenital Abnormalities and Physical Phenotype in Patients with Diamond–Blackfan Anemia May Be Overlooked

Objective: Diamond–Blackfan anemia (DBA) is a rare and inherited form of erythroid aplasia, characterized by severe macrocytic anemia, congenital malformations, and predisposition to cancer.
Şule Ünal, Nihan Avcu Oral, Pelin Özlem Şimşek Kiper, Fatma Gümrük, Gulare Soltanova, Ünal, Şule, ŞİMŞEK KİPER, PELİN ÖZLEM, Soltanova, Gulare, ORAL, NİHAN, Avcu Oral, Nihan, Gümrük, Fatma, Özlem Şimşek Kiper, Pelin   +11 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

ORAL PARAFUNCTIONAL HABITS AMONG PRESCHOOL CHILDREN IN UKRAINE: A SINGLE-CENTER LONGITUDINAL STUDY

Український стоматологічний альманах
Objective. This study aims to investigate the prevalence of harmful oral habits in children before and after the full-scale invasion of Ukraine, to examine the efficacy of the Froggy Mouth myofunctional rehabilitation approach for atypical swallowing ...
N.P. Makhlynets, D.B. Plishka, M.B. Kokoshko, Z.R. Ozhohan, N.M. Kozan   +4 more
doaj   +1 more source

Surgery-induced iris abnormalities after Descemet membrane endothelial keratoplasty and their impact on postoperative clinical outcomes

, 2019
Natsuko Mori,1,2 Hideaki Yokogawa,1 Akira Kobayashi,1 Tsubasa Nishino,1,3 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan; 2Department of Ophthalmology, Saiseikai Kanazawa Hospital ...
Kobayashi A, Mori N, Yokogawa H, Sugiyama K, Nishino T   +4 more
core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Systemic abnormalities associated with retinal vein occlusion in young patients

, 2017
Suthasinee Sinawat,1 Chavisa Bunyavee,2 Tanapat Ratanapakorn,1 Supat Sinawat,3 Wipada Laovirojjanakul,1 Yosanan Yospaiboon1 1KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of ...
Yospaiboon Y, Bunyavee C, Sinawat S, Laovirojjanakul W, Ratanapakorn T   +4 more
core  

Structural abnormalities in Paraguayan southern three-banded armadillos Tolypeutes matacus (Chlamyphoridae)

Two structural abnormalities are reported in southern three-banded armadillos Tolypeutes matacus (Chlamyphoridae) from Paraguay. Additional reports of individuals with amputated legs are noted, and a potential explanation for the frequency of such ...
Paul Smith
core   +1 more source

Psoriasis rupioides with marked nail abnormalities in a HIV-positive patient

, 2016
Introduction. Psoriasis rupioides is a rare type of psoriasis. Although a description of it is easy to find in most textbooks of psoriasis, it does not have a place in the ICD-10 classification, and there have been very few case reports published in ...
Iwona Chlebicka, Adam Reich, Jacek Szepietowski   +2 more
core   +1 more source

Brain structural and neurofunctional correlates of liability to psychosis : a multimodal neuroimaging approach [PDF]

, 2011
Schizophrenia is one of the most debilitating and still not entirely understood mental diseases. Improvements in the treatment came hand in hand with an introduction of antipsychotics and thus with better understanding of neurobiology underlying its ...
Smieskova, Renata
core   +1 more source