Results 91 to 100 of about 549,661 (323)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Pengaruh Sari Buah Merah (Pandanus conoideus Lam) terhadap Abnormalitas Spermatozoa Ayam Kampung

open access: yesJurnal Ilmu Peternakan dan Veteriner Tropis, 2021
Antioxidants are substances that can prevent the occurrence of free radical antioxidation reactions in lipid oxidation.  Red fruit (Pandanus conoideus Lam) is one of the plants endemic to Papua which contain high antioxidant.
Angelina Novita Tethool   +2 more
doaj  

Abnormal Object Recognition: A Comprehensive Study [PDF]

open access: yesarXiv, 2014
When describing images, humans tend not to talk about the obvious, but rather mention what they find interesting. We argue that abnormalities and deviations from typicalities are among the most important components that form what is worth mentioning.
arxiv  

Computer Vision and Abnormal Patient Gait Assessment a Comparison of Machine Learning Models [PDF]

open access: yesarXiv, 2020
Abnormal gait, its associated falls and complications have high patient morbidity, mortality. Computer vision detects, predicts patient gait abnormalities, assesses fall risk and serves as clinical decision support tool for physicians. This paper performs a systematic review of how computer vision, machine learning models perform an abnormal patient's ...
arxiv  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Monitoring egg fertility, embryonic morbidity, and mortality in an oviparous elasmobranch using ultrasonography

open access: yesFrontiers in Veterinary Science
Ultrasonography is widely used to monitor pregnancy in viviparous species, but it is underutilized as a tool to characterize embryonic development in oviparous species.
Lance Adams   +7 more
doaj   +1 more source

Automating Abnormality Detection in Musculoskeletal Radiographs through Deep Learning [PDF]

open access: yesarXiv, 2020
This paper introduces MuRAD (Musculoskeletal Radiograph Abnormality Detection tool), a tool that can help radiologists automate the detection of abnormalities in musculoskeletal radiographs (bone X-rays). MuRAD utilizes a Convolutional Neural Network (CNN) that can accurately predict whether a bone X-ray is abnormal, and leverages Class Activation Map (
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

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