Results 111 to 120 of about 549,661 (323)
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Toward a Taxonomy and Computational Models of Abnormalities in Images [PDF]
arXiv, 2015 The human visual system can spot an abnormal image, and reason about what makes it strange. This task has not received enough attention in computer vision. In this paper we study various types of atypicalities in images in a more comprehensive way than has been done before.
arxiv
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Koncept dětské abnormality v 19. století
Theatrum Historiae, 2013 The article deals with the perception of the abnormality of children in 19.th century. The first part concerns the theoretical view of enlightenment and the view of philanthropists and the searching of the causes of abnormality.
Martina Halířová
doaj
Congenital Abnormalities of the Uterus and Pregnancy [PDF]
, 1956 John A. Holmes
openalex +1 more source
FEBS Open Bio, EarlyView.ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren +8 more
wiley +1 more source
Training Medical Large Vision-Language Models with Abnormal-Aware Feedback [PDF]
arXivExisting Medical Large Vision-Language Models (Med-LVLMs), which encapsulate extensive medical knowledge, demonstrate excellent capabilities in understanding medical images and responding to human queries based on these images. However, there remain challenges in visual localization in medical images, which is crucial for abnormality detection and ...
arxiv
Abnormality in Tropæolum [PDF]
Nature, 1889 IN the early summer of last year my attention was directed to a case of abnormality in flowers of Tropaeolum, which I think is sufficiently interesting and rare to be worthy of record.
openaire +3 more sources
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Fine-grained Abnormality Prompt Learning for Zero-shot Anomaly Detection [PDF]
arXivCurrent zero-shot anomaly detection (ZSAD) methods show remarkable success in prompting large pre-trained vision-language models to detect anomalies in a target dataset without using any dataset-specific training or demonstration. However, these methods are often focused on crafting/learning prompts that capture only coarse-grained semantics of ...
arxiv