Results 131 to 140 of about 75,141 (304)
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster +9 more
wiley +1 more source
Abstract Background Umbilical cord blood (UCB) is a rich source of hematopoietic stem and progenitor cells for regenerative medicine. This study characterized the cellular composition of UCB from twin pregnancies to identify blood type concordance (BTC)‐related differences.
Van‐Tinh Nguyen +8 more
wiley +1 more source
Abstract Background Field transfusion of whole blood is vital for patients in hemorrhagic shock, particularly in austere or resource‐limited environments. Military use of warm fresh whole blood (WFWB) has inspired civilian interest in walking blood banks (WBBs) for rural, prehospital, and mass casualty settings where blood product access is limited ...
Christian Gerhardus +19 more
wiley +1 more source
Genetic diversity in RHD and RHCE genes among a selected Kenyan blood donor population
Abstract Background Serologic typing for ABO and RhD is standard in transfusion services, with extended serology and genotyping performed to reduce red cell alloimmunization risk. In Kenya, RH typing is limited to RhD, and genotyping is unavailable. This study used RHD/RHCE genotyping to predict phenotypes and their distribution in a Kenyan blood donor
Sandra A. Sowah +8 more
wiley +1 more source
Genetic analysis of cases from a family with reduced B antigen expression in ABO blood group system
[Objective] To classify the ABO blood group phenotypes of 5 cases from a family, and to explore the molecular mechanism for reduced B antigen expression in ABO blood group system.
ZHOU Taimei +5 more
doaj +1 more source
Abstract Background A minority of blood donors are Rh(D)‐negative, and Rh(D)‐negative red blood cell (RBC) products are often overutilized. As such, Rh(D)‐negative RBCs may be difficult to maintain in blood bank inventory. Study Design and Methods We changed our blood bank laboratory policy to approve non‐alloimmunized Rh(D)‐negative patients to ...
Julie Katz Karp +5 more
wiley +1 more source
Abstract Background Substituting group A whole blood (GAWB) might relieve some of the burden on the low titer group O whole blood (LTOWB) inventory. This simulation examined the effect of implementing GAWB at a large trauma hospital. Study Design and Methods A civilian trauma center with LTOWB and GAWB par levels set to 22 and 10 units, respectively ...
Emilie A. Jochumsen +6 more
wiley +1 more source
Abstract Background The BORN trial suggested that using cord blood‐red blood cells (CB‐RBCs) to transfuse severely preterm neonates significantly improves clinical outcomes compared to standard adult donor RBCs (A‐RBC). Study Design and Methods The study illustrates CB‐RBC concentrate production and inventory management across nine CB banks ...
Claudio Pellegrino +38 more
wiley +1 more source
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza +11 more
wiley +1 more source

