Results 141 to 150 of about 1,132,735 (361)
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher +7 more
wiley +1 more source
Study on the Bw11 subtype caused by the 695 T>C mutation in exon 7 of the ABO blood group gene [PDF]
Objective To identify the rare ABO*BW.11/ABO*O.01.02 subtype in the Yi ethnic group in China, and to investigate the blood group serological characteristics, molecular mechanisms, and genetic background of the ABO*BW.11/ABO*O.01.02 subtype.
ZHOU Lihua, SHEN Ru, QU Kexuan, WANG Aihua, CHEN Youhui, YUAN Zhimin
doaj +1 more source
Comparison of printed glycan array, suspension array and ELISA in the detection of human anti-glycan antibodies [PDF]
Anti-glycan antibodies represent a vast and yet insufficiently investigated subpopulation of naturally occurring and adaptive antibodies in humans. Recently, a variety of glycan-based microarrays emerged, allowing high-throughput profiling of a large ...
Bovin, Nicolai +9 more
core
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Abstract Diabetes is a leading cause of kidney failure, and individuals with both diabetes and chronic kidney disease (CKD) experience significantly higher rates of complications and mortality. The international guideline developer Kidney Disease: Improving Global Outcomes (KDIGO) has produced clinical practice guidelines that reflect recent advances ...
Hannah Wallace +21 more
wiley +1 more source
ABSTRACT Aim To explore the key knowledge, skills, attributes and organisational support that nurses require to optimise their scope of practice when providing care to people experiencing homelessness. Design A qualitative descriptive study exploring nurses' scope of practice for addressing health needs of people experiencing homelessness.
Olivia Hollingdrake +4 more
wiley +1 more source
Invalid Forensic Science Testimony and Wrongful Convictions [PDF]
This is the first study to explore the forensic science testimony by prosecution experts in the trials of innocent persons, all convicted of serious crimes, who were later exonerated by post-conviction DNA testing.
Garrett, Brandon L., Neufeld, Peter J.
core +2 more sources
Molecular mechanism of ABO bood group variation
Objective To study the relationship between ABO subtype, para-Bombay blood group and genotype, so as to explore the possible molecular mechanism of these two blood groups, and provide accurate genetic detection targets and theoretical basis for the ...
Hang LEI +4 more
doaj +1 more source

