Results 1 to 10 of about 2,117,746 (268)

ANTIBODIES TO ACETYLCHOLINESTERASE [PDF]

open access: yesProceedings of the National Academy of Sciences, 1969
A rabbit antiserum against commercially available Electrophorus electricus acetylcholinesterase has been prepared. Five precipitation bands were distinguished by immunoelectrophoresis, but only three of these contained demonstrable enzyme activity.
openaire   +2 more sources

The whole genomic analysis of orf virus strain HN3/12 isolated from Henan province, central China

open access: yesBMC Veterinary Research, 2017
Background The Orf virus (ORFV) is the causative agent of orf, a globally-occurring, acute, pustular, contagious disease affecting sheep, goats and humans with a worldwide distribution. Currently, the genomic analysis of four ORFV strains from the Fujian
Huiqin Chen   +7 more
doaj   +1 more source

Antibody and Antibody Mimetic Immunotherapeutics [PDF]

open access: yesFuture Medicinal Chemistry, 2017
Angeline N, Ta, Brian R, McNaughton
openaire   +2 more sources

Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2

open access: yesFrontiers in Immunology
IntroductionThe emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic.
Peng Yu   +9 more
doaj   +1 more source

Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease

open access: yesScientific Reports
Shikonin (SHK) is a plant-derived naphthoquinone known for its anti-inflammatory activity, though the mechanism remains largely unexplored. The NLRP3 inflammasome, one of the most studied inflammasomes, can cause uncontrolled inflammation and drive ...
Jing Huang   +11 more
doaj   +1 more source

CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis

open access: yesScientific Reports, 2017
CLEC14a (C-type lectin domain family 14 member) is a tumor endothelial cell marker protein that is known to play an important role in tumor angiogenesis, but the basic molecular mechanisms underlying this function have not yet been clearly elucidated. In
Jihye Jang   +6 more
doaj   +1 more source

Death by antibody

open access: yesBMJ Case Reports, 2019
A 42-year-old woman with a background of psoriatic arthritis presented with a 7-day medical history of fevers of unknown source; she had recently undergone elective shoulder arthroscopy, and her medications included anti-interleukin 17A (anti-IL-17A) drug, secukinumab.
Timothy Faccini   +2 more
openaire   +3 more sources

Diminished but Not Abolished Effect of Two His351 Mutants of Anthrax Edema Factor in a Murine Model

open access: yesToxins, 2016
Edema toxin (ET), which is composed of a potent adenylate cyclase (AC), edema factor (EF), and protective antigen (PA), is one of the major toxicity factors of Bacillus anthracis.
Taoran Zhao   +10 more
doaj   +1 more source

Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1

open access: yesSignal Transduction and Targeted Therapy, 2023
Chunyun Sun   +9 more
doaj   +1 more source

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

open access: yesFrontiers in Immunology, 2019
Myeloid-derived suppressor cells (MDSCs) play crucial roles in tumorigenesis and their inhibition is critical for successful cancer immunotherapy.
Dehong Yan   +10 more
doaj   +1 more source

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