Results 11 to 20 of about 2,528,348 (198)
Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]
, 2013 Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L +26 more
core +1 more source
IgG Fc engineering to modulate antibody effector functions
Protein & Cell, 2017 Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions.
Xinhua Wang +2 more
doaj +1 more source
Methods and Protocols, 2021 Despite the public availability, finding experts in any field when relying on academic publications can be challenging, especially with the use of jargons.
Wei-Ling Wu +5 more
doaj +1 more source
Monoclonal Antibody-Directed Therapy [PDF]
, 2022 The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered.
core +1 more source
Frontiers in Microbiology, 2023 Instruction: Rift valley fever virus (RVFV) is a mosquito-transmitted bunyavirus that causes severe disease in animals and humans. Nevertheless, there are no vaccines applied to prevent RVFV infection for human at present.
Meng Hao +10 more
doaj +1 more source
The Role of Antibody-Based Therapies in Neuro-Oncology [PDF]
, 2023 This review explores the evolving landscape of antibody-based therapies in neuro-oncology, in particular, immune checkpoint inhibitors and immunomodulatory antibodies.
Jing Sun +9 more
core +1 more source
Challenges and developments in universal vaccine design against SARS-CoV-2 variants
npj Vaccines, 2022 The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had become a global concern because of its unexpectedly high pathogenicity and transmissibility.
Fangxin Zhao +4 more
doaj +1 more source
Antibodies and antibody-derived analytical biosensors [PDF]
Essays in Biochemistry, 2016 The rapid diagnosis of many diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Biosensors are now being applied for rapid diagnostics due to their capacity for point-of-care use with minimum need for operator input.
Sharma, Shikha +2 more
openaire +2 more sources
Antibody Conjugation and Formulation [PDF]
, 2019 In an era where ultra-high antibody concentrations, high viscosities, low volumes, auto-injectors, and long storage requirements are already complex problems with the current unconjugated monoclonal antibodies on the market the formulation demands for ...
Alves, Nathan J.
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A comprehensive proteogenomic study of the human Brucella vaccine strain 104 M
BMC Genomics, 2017 Background Brucella spp. are Gram-negative, facultative intracellular pathogens that cause brucellosis in both humans and animals. The B. abortus vaccine strain 104 M is the only vaccine available in China for the prevention of brucellosis in humans ...
Xiaodong Zai +12 more
doaj +1 more source