Results 91 to 100 of about 204,159 (347)

Empirical research related to the ethics of pragmatic clinical trials: A scoping review

Learning Health Systems, EarlyView.
Abstract Background Pragmatic clinical trials (PCTs) offer insights into real‐world intervention effectiveness, but they may involve challenging ethical issues. Empirical ethics research may inform deliberations about them. Methods We conducted a scoping review of empirical ethics research related to PCTs.
Kayla R. Mehl, Stephanie R. Morain, Jeremy Sugarman   +2 more
wiley   +1 more source

The Potential Significance of ABO Genotyping for Donor Selection in Kidney Transplantation

Frontiers in Immunology, 2020
BackgroundThe ABO blood group system is clinically important in kidney transplantation, but ABO genotyping fails to attract sufficient attention in some countries and regions.
Yi Zhou, Yuchen Wang, Haiqiang Ni, Wenfeng Deng, Ding Liu, Jian Xu, Naiqian Cui, Yihan Wu, Shaojie Fu, Lulu Xiao, Hailiang Liu, Ka Qi, Shaoqing Wang, Fu Xiong, Yun Miao   +14 more
doaj   +1 more source

Using Machine Learning to Predict Acute Graft‐Versus‐Host Disease in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: Integration of Clinical and Genetic Factors

Medicine Advances, EarlyView.
This study successfully developed and validated machine learning models to predict acute graft‐versus‐host disease (aGVHD) in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation. These models, particularly the best‐performing one, facilitated early identification of high‐risk patients, enabling clinicians to provide ...
Xianggui Wang, Xiujuan Chen, Yan Li, Sha Liu, Yuhua Qu, Qingling Gu, Haojie Qiu, Qiongbo Huang, Yousi Miao, Min Huang, Hua Jiang, Jiali Li, Xiaolan Mo   +12 more
wiley   +1 more source

Genetic Analysis of ABO and Rh Blood Groups in Backward Caste Population of Uttar Pradesh, India

Notulae Scientia Biologicae, 2011
A series of glycoproteins and glycolipids on red blood cell surface constitute blood group antigens. These are AB, A, B and O in ABO blood group system and Rh in rhesus blood group system.
Vandana RAI, Pradeep KUMAR
doaj   +3 more sources

Characterization of Visceral Adipose Tissue Proteome Reveals Metabolic Changes and Inflammatory Signatures in Severe Obesity

Obesity, EarlyView.
ABSTRACT Objective Severe obesity poses a major public health concern due to its links with cardiometabolic complications and mortality. Visceral adipose tissue (VAT) plays a key role in these processes through distinct molecular features. This study aimed to characterize the VAT proteome of individuals with severe obesity and investigate its ...
Prince Dadson, Miikka‐Juhani Honka, Tomi Suomi, Anne Rokka, Saila Kauhanen, Paulina Salminen, Mika Helmiö, Peter James, Laura L. Elo, Vesa M. Olkkonen, Pirjo Nuutila   +10 more
wiley   +1 more source

Distribution of ABO, Rh, and MNS blood groups from students in Walailak University, Thailand: A descriptive cross-sectional study

Clinical Epidemiology and Global Health
Background: The presence or absence of blood group antigens can lead to alloimmunization, causing hemolytic transfusion reactions and hemolytic disease of the fetus and newborn. The distribution of these antigens varies among different ethnic populations,
Thitinat Duangchan, Nadia Suklim, Virakan Pornpisanvijit, Saranporn Ratmunee, Thunyaluk Plyduang, Nateelak Kooltheat, Nurdina Charong   +6 more
doaj   +1 more source

Connection of the ABO blood group system from the whole blood groups with the diabetes mellitus typ 2 for the period 2005-2009 [PDF]

, 2011
Introduction:The real dimension of the connection between any blood group from the ABO system of blood groups and diabetes mellitus typ 2 in the eastern part of Republic of Macedonia in not well known.
Janevik-Ivanovska, Emilija, Kamcev, Nikola, Kamceva, Gordana, Kamceva, Milka   +3 more
core  

A Correlation Study of Hypertension and Abo Blood Group System at Tertiary Care Hospital. [PDF]

Introduction: Hypertension is the major public health issue globally, contributing to a high incidence of cardiovascular diseases. The ABO blood group system has been studied in various contexts for its potential association with several diseases, but ...
Ravi Teja CN, Divya N.S, Vanisri H.R, K.T Athulya Krishna Kumar, Dhara Sreedhar, Patel Saurabh Dineshbhai
core   +2 more sources

Validation of a Polymerase Chain Reaction technique for Kidd blood group genotyping [PDF]

, 2015
The Kidd blood group antigens, Jkª and Jkᵇ , are two of the main surface markers which are found on the membrane of red blood cells. The determination of whether a donor or a recipient has the Jkª and/or the Jkᵇ antigens is crucially important to ...
Borg, Joseph J., Debono, Jesmond, Xuereb, Karl   +2 more
core   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source