Results 111 to 120 of about 8,663,854 (292)

A case of special blood type with discrepancy between ABO genotype and serological results

[Objective] To analyze the cause of discrepancy between ABO genotype B102/O01 and serological results in one case by PCR-SSP, to clarify the serological characteristics of this special blood group, and to explore relevant blood transfusion strategies ...
CUI Limin, ZHANG Wei, JIA Wenting
core   +1 more source

Defining the role of αC helix interactions in the activation of the integrin αI domain

The FEBS Journal, EarlyView.
The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö, Tomi T. Airenne, Jarmo Käpylä, Hongmin Tu, Eva Bligt‐Lindén, Vimal Parkash, Jyrki Heino, Tiina A. Salminen   +7 more
wiley   +1 more source

DR3 is associated with type 1 diabetes and blood group ABO incompatibility

, 2002
Type 1 diabetes is associated with autoimmunity against pancreatic β cells. ABO incompatibility is associated with ABO immunization during pregnancy. Type 1 diabetes is associated with certain HLA DR and DQ haplotypes.
Sanjeevi, C. B.,, Berzina, L.,, Shtauvere-Brameus, A.,, Saduaskaite-Kühne, Vaiva,, Ludvigsson, Johnny,, Nelson, Nina,   +5 more
core   +1 more source

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Relation between ABO blood groups and Helicobacter pylori infection in symptomatic patients

, 2011
Mohamad Salih Jaff Pathology Department, College of Medicine, Hawler Medical University (formerly Salahuddin University), Erbil, Kurdistan Region, Iraq Abstract: Epidemiological studies have demonstrated higher frequencies of the O blood group and the ...
Jaff MS
core  

B blood type indicates poorer overall survival in patients with severe burn injuries: a case-control study

Annals of Medicine
Introduction This study focuses on the prognostic impact of ABO blood type in patients with severe burn injuries, particularly following the Kunshan explosion, exploring an under-investigated area of burn injury outcomes.Method Data from patients ...
Wei Zhang, Xinru Wu, Yifan Liu, Yuntao Yao, Xirui Tong, Linhui Li, Dayuan Xu, Junqiang Li, Shuyuan Xian, Hanlin Sun, Jiale Yan, Guosheng Wu, Long Xu, Bingnan Lu, Runzhi Huang, Shizhao Ji, Zhaofan Xia   +16 more
doaj   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Distribution characteristics of dyslipidemia in ABO blood groups in Suburbs of Shanghai, China: A cross-sectional study

Science Progress
Objective To investigate the distribution features of dyslipidemia within the ABO blood group system Suburbs of Shanghai, China. Methods This retrospective cross-sectional study analyzed 12,926 sets of blood lipid data associated with the ABO blood group
Jing Chen, Shanshan Chen, Tao Xiao
doaj   +1 more source

At the heart of home‐based care: multidisciplinary heart failure management in a quaternary centre's community programmes

Internal Medicine Journal, EarlyView.
Abstract Background Heart failure (HF) is a frequent cause of hospital admissions, carrying a high risk of hospital readmission and mortality. Alfred Health General Medicine Hospital in the Home (GM‐HITH) and Hospital Admission Risk Program (HARP) offer multidisciplinary HF care to multimorbid patients in bed‐substitution and non‐admitted community ...
Elana Forbes, Ingrid Hopper, Cathy Corbett, Felice Borghmans, Emma O'Donnell, Ana Slavnic, Genevieve Harvey, Elizabeth Rochford, Archana Thayaparan   +8 more
wiley   +1 more source