Characterization of ABH-subtype donor-specific antibodies in ABO-A-incompatible kidney transplantation [PDF]
American Journal of Transplantation, 2021 ABO-incompatible (ABOi) transplantation requires preemptive antibody reduction; however, the relationship between antibody-mediated rejection (AMR) and ABO-antibodies, quantified by hemagglutination (HA), is inconsistent, possibly reflecting variable graft resistance to AMR or HA assay limitations.
Andrew Bentall +10 more
semanticscholar +5 more sources
ABH-Glycan Microarray Characterizes ABO Subtype Antibodies: Fine Specificity of Immune Tolerance After ABO-Incompatible Transplantation [PDF]
American Journal of Transplantation, 2016 Organ transplantation from ABO blood group-incompatible (ABOi) donors requires accurate detection, effective removal and subsequent surveillance of antidonor antibodies. Because ABH antigen subtypes are expressed differently in various cells and organs, measurement of antibodies specific for the antigen subtypes in the graft is essential.
M, Jeyakanthan +21 more
semanticscholar +5 more sources
Rapid and Cost-Effective ABO Blood Genotyping Using a Freeze-Dried, Point-of-Care Ready Loop-Mediated Isothermal Amplification (LAMP) Assay [PDF]
DiagnosticsBackground: The accurate and rapid genotyping of ABO (chromosome 9q34.2) blood types is critical for clinical diagnostics and transfusion medicine, particularly in scenarios where serological methods yield uncertain results, such as in neonatal testing ...
Jianlin Zhang +3 more
doaj +3 more sources
Identification of a novel ABO*O.01.01 allele with c.801G>T mutation in a Chinese A2 subtype individual. [PDF]
Blood Transfus,
Xu C, Zhu Z, Zhu M, Xu W.
europepmc +4 more sources
ABO, D Blood Typing and Subtyping Using Plug-Based Microfluidics [PDF]
Analytical Chemistry, 2008 A plug-based microfluidic approach was used to perform multiple agglutination assays in parallel without crosscontamination and using only microliter volumes of blood.
Ismagilov, Rustem F. +3 more
core +5 more sources
Identification and analysis of a novel A allele with a c.565A > G variant on the ABO*A1.02 allele leading to subtype A: A case report. [PDF]
Medicine (Baltimore)Rationale: The ABO blood group system typically includes 4 phenotypes: type A, type B, type O, and type AB. ABO subtypes refer to further subdivisions within these 4 blood types.
Lu W, Mo C, Zhong J, Zhang Y, Li L.
europepmc +2 more sources
Molecular mechanism of a novel Aweak subtype in Chinese pedigrees: identification and analysis of a large genomic deletion in the promoter upstream distal region of the ABO gene. [PDF]
Blood TransfusBackground Accurate ABO typing is essential for transfusion safety, yet weak A/B subgroups continue to present diagnostic challenges. Although most weakened ABO antigen expressions are linked to missense mutations or small indels within coding regions ...
Liu J +5 more
europepmc +2 more sources
AwB subtype caused by a novel ABO *A allele and its molecular mechanisms [PDF]
Zhenduanxue lilun yu shijian, 2021 Objective: To investigate the molecular mechanism of AwB subtype by performing serological and gene detection in a Chinese individual. Methods: One case of AwB subtype was determined by ABO serology using standard serological method, and 7 exons of ABO ...
ZHOU Lu, LEI Hang, HONG Ye, JIN Shuang, DONG Yongqin, WANG Xuefeng, CAI Xiaohong
doaj +2 more sources
Six splice site variations, three of them novel, in the ABO gene occurring in nine individuals with ABO subtypes [PDF]
Journal of Translational Medicine, 2021 Background Nucleotide mutations in the ABO gene may reduce the activity of glycosyltransferase, resulting in lower levels of A or B antigen expression in red blood cells.
Xiaozhen Hong +6 more
doaj +3 more sources