Results 181 to 190 of about 32,919 (252)

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

The Power of Hope in the Movements for Freedom: An Interview with Robin D. G. Kelley

Transatlantica
Charlotte Recoquillon, Robin D. G. Kelley   +1 more
doaj   +1 more source

Ultrasound-Based SECURED Protocol for Central Venous Catheterization: A Feasibility Study. [PDF]

Biomed Res Int
Choi MS, Do HH, Lee JH, Lee SC, Lee S.
europepmc   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Intracardiac echocardiography guided anatomical approach to cardioneuroablation: feasibility and outcomes. [PDF]

Europace
Farwati M, Hussein AA, Giraldo S, Bautista W, Higuchi K, Baranowski B, Bhargava M, Callahan TD, Chung MK, Chung R, Younis A, Courson J, Dresing TJ, Kanj M, Kochar A, Koeth R, Lee JZ, Liuba I, Martin DO, Mayuga K, Nakhla S, Rickard J, Saliba WI, Sroubek J, Taigen TL, Varma N, Witten J, Soltesz E, Tapias C, Saenz L, Wazni O, Santangeli P.   +31 more
europepmc   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Attitudes Toward Prostitution in Norway, Spain, and Germany: Association With the Legal Context and Susceptibility to Persuasion. [PDF]

Scand J Psychol
Megías JL, Thon PR, Siebler F, Bohner G.   +3 more
europepmc   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source