Results 11 to 20 of about 31,334 (207)

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi-Omics Approach to Unravel the Mechanism. [PDF]

Adv Sci (Weinh)
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Wang L, Li Z, Hu T, Li Q, Zhang L, Mei X, Qi X, Liu S, Kong W, Luo J, Wu A, Huang F, Li S, Dai S, Zhang C, Li R, Wu J.   +16 more
europepmc   +2 more sources

Low-Intensity Pulsed Ultrasound Promotes Osteogenesis in Porous Titanium Alloys Through miR-1187/BMP4 Pathway. [PDF]

FASEB J
The Schematic of LIPUS promotes osteogenesis of porous titanium alloys through inhibiting miR‐1187 and upregulating BMP4. ABSTRACT The repair of critical‐sized bone defects remains a significant clinical challenge. Low‐intensity pulsed ultrasound (LIPUS), in combination with porous titanium alloy (PTi) scaffolds, has emerged as a promising therapeutic ...
Qin L, Cao H, Liu X, Zhang D, Wu L.
europepmc   +2 more sources

First‐line Treatment With Bendamustine and Rituximab for Old and Frail Patients With Aggressive Lymphoma: Results of the B‐R‐ENDA Trial

HemaSphere, Volume 6, Issue 12, December 2022., 2022
The incidence of aggressive B‐cell lymphomas increases with age, but for elderly or frail patients not eligible for doxorubicin‐containing treatment standard therapy remains to be defined. In this prospective, multicenter, phase‐2 B‐R‐ENDA trial, we investigated the feasibility, toxicity, and efficacy of 8 cycles rituximab combined with 6 cycles ...
Friederike Braulke, Florian Zettl, Marita Ziepert, Andreas Viardot, Christoph Kahl, Gabriele Prange‐Krex, Agnieszka Korfel, Martin Dreyling, Alexander Bott, Ulrich Wedding, Dietmar Reichert, Maike de Wit, Frank Hartmann, Viola Poeschel, Norbert Schmitz, Mathias Witzens‐Harig, Wolfram Klapper, Andreas Rosenwald, Gerald Wulf, Bettina Altmann, Lorenz Trümper   +20 more
wiley   +1 more source

Morphological Characteristics and Correction of Long Tubular Bone Regeneration under Chronic Hyperglycemia Influence

Analytical Cellular Pathology, Volume 2020, Issue 1, 2020., 2020
Introduction. Unsatisfactory consequences of bone regeneration disorders in diabetes mellitus (DM) patients, their high prevalence, complication number, and difficulties in treatment require further study and deeper understanding of reparative osteogenesis mechanisms under chronic hyperglycemia and finding new effective and affordable approaches to ...
Yevhenii S. Dudchenko, Olena S. Maksymova, Vasyl S. Pikaliuk, Dmytro V. Muravskyi, Ludmila I. Kyptenko, Gennadii F. Tkach, Giovanni Tuccari   +6 more
wiley   +1 more source

Inovasi Pengolahan Ikan Tuna Menjadi Abon

Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat, 2022
Gampong Kuala Langsa is one of the abundant fish-producing areas in Langsa city, some of the people make a living as fishermen so that in that area the number of fish is very large. So far, the surrounding community only sells the fish directly, so often there are still fish left that have not been sold, so a method or method is needed to increase ...
Nurlaila Handayani, Yusri Nadya, Nina Fahriana   +2 more
openaire   +1 more source

DIVERSIFIKASI PENGOLAHAN KULIT NANAS MENJADI ABON

MEDIAGRO, 2022
Kulit nanas merupakan limbah buah yang jumlahnya cukup melimpah. Pengolahan limbah kulit nanas menjadi produk pangan merupakan salah satu upaya diversifikasi untuk meningkatkan nilai limbah kulit buah. Salah satu produk olahan kulit nanas adalah abon yang umumnya dibuat dari daging.
Afif Kholifah, Zenny Zanuba Arifah, Ika Widyaningrum, Iffah Muflihati, Sari Suhendriani   +4 more
openaire   +1 more source

Televizyonun Değişen Yüzü: Twitch TV ve Yeni Nesil Yayıncılık

Selçuk İletişim, 2022
Televizyon ve internet tabanlı video platformlarının birer rakip olarak düşünüldüğü dönemin ardından, özellikle 2010 yılından itibaren televizyon yayıncılığı internet ortamında yer almaya ve içeriklerini farklı mecralar üzerinden paylaşmaya başlamıştır ...
Ergin Şafak Dikmen
doaj   +1 more source

Model and Technique for Abonent Address Masking in Cyberspace

Voprosy kiberbezopasnosti, 2020
Regulators charge to counter information security threats against the structural and functional characteristics of the information system to ensure the information security requirements. These requirements include information system structure and composition, information technologies and functioning characteristics, physical and logical, functional and
Vadim Kuchurov, Roman Maximov, Roman Sherstobitov   +2 more
openaire   +1 more source

Ajans Gazeteciliği ve Medya Sektöründe Haber Ajanslarının Etkinliği

İletişim Kuram ve Araştırma Dergisi, 2014
ÖZETKitle iletişim araçlarının kurumsal haber kaynakları arasında yer alan haber ajansları, kapasite ve etkinliğini giderek artırmaktadır. Bu kapasite artışı, medyanın haber tedarikçisi olan ajanslar için önemli bir başarıdır.
Muzaffer - Şahin
doaj   +4 more sources

BÜYÜKŞEHİR SU VE ATIKSU İDARELERİNİN VERİMLİLİKLERİNİN VERİ ZARFLAMA ANALİZİ İLE ÖLÇÜMÜ - ATA ENVELOPMENT ANALYSIS MEASUREMENT OF PRODUCTIVITY OF MUNICIPALITIES WATER AND WASTE WATER ADMINISTRATIONS

Mehmet Akif Ersoy Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018
Verimlilik ve etkinlik çalışmaları dünyada her geçen gün artmaktadır. Türkiye’de de verimlilik çalışmalarının öneminin kavranmasıyla birlikte çalışma sayılarında kayda değer bir artış olmuştur. Türkiye’de kamusal alanda verimlilik analizi çalışmaları ise
Durmuş Acar, Gürkan Koç
doaj   +1 more source