Results 111 to 120 of about 107,451 (261)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Seeding success for Aboriginal students

open access: yes, 2006
Despite a willingness by stakeholders to address Aboriginal education disadvantage and recent successes in outcomes, Australian education largely continues to fail to provide Aboriginal Australians with commensurate educational outcomes and life ...
Craven, Rhonda
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Aboriginal expenditure patterns: An analysis of empirical data and its policy implications [PDF]

open access: yes, 1991
Assessments of the adequacy of government social security programs, of taxation policy, the equity of income distribution and of the impact on Australian households of changing economic conditions all rely heavily on expenditure data obtained from ...
Smith, Diane E
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

First counts, 1991 Census: A comment on Aboriginal and Torres Strait Islander population growth [PDF]

open access: yes, 1992
Due to a lack of accurate data on the size, distribution and trends in the Aboriginal and Torres Strait Islander populations in different geographic regions, past census data cannot be used for policy planning, administion or other uses.
Gaminiratne, K. H. W.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Indigenous housing need [PDF]

open access: yes, 2012
This paper provides an update of the evidence on different aspects of the housing situation of Indigenous Australians. By using a regional approach, it is possible to get a sense of how the housing circumstances of the population vary across our ...
Nicholas Biddle, Biddle, Nicholas
core  

An Aboriginal Moomba: Out of the Dark'

open access: yes, 1951
The Australian Aboriginal League presents its contribution to the Centenary of Victoria and Jubilee of the Commonwealth celebrations.
Australian Aboriginal League
core   +1 more source

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