Results 41 to 50 of about 91,089 (313)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Aboriginal professionals: work, class and culture [PDF]
, 2013 This paper considers the increasing representation of Indigenous people in professional occupations. While the predominant focus in Australian scholarship remains contexts of Aboriginal disadvantage, there is a steadily increasing number of Indigenous
Lahn, Julie, Julie Lahn
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Community participation agreements: a model for welfare reform from community-based research [PDF]
, 2001 Summary In its June 2001 budget, the Federal Government announced a new framework for welfare reform, Australians Working Together. One component of the framework is the proposed development of Community Participation Agreements in remote Indigenous ...
Diane Smith, Smith, Diane E
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Economic value of Aboriginal community controlled health services [PDF]
, 2014 Summary: This report provides evidence that Aboriginal health services run by Aboriginal people: Provide jobs for more than 3,200 Aboriginal people (over 5,000 in total) and are the main source of Aboriginal employment in many communities;
Katrina Alford
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International Journal of Circumpolar Health, 2018 The aim of this study was to determine and compare the prevalence of pre-diabetes and type 2 diabetes mellitus (T2DM) among Sami and non-Sami men and women of rural districts in Northern Norway.
Ali Naseribafrouei +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The Power of Data in Aboriginal Hands [PDF]
, 2012 TThis Topical Issue presents the the text prepared by Peter Yu as the opening pleniary paper at the conference Social Science Perspectives on the 2008 National Aboriginal and Torres Strait Islander Social Survey, held at The Australian National ...
Yu, Peter +1 more
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