Results 61 to 70 of about 107,451 (261)
From Linguistic Research Findings to Useful Products for Australian Aboriginal Communities
As a linguist investigating the Warlpiri language of central Australia since 1975 and the Waanyi language of the Gulf of Carpentaria region since 2000, my research has always had dual goals.
Mary Laughren
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Let’s talk about success: exploring factors behind positive change in Aboriginal communities [PDF]
What are the factors that enable some Aboriginal organisations to drive positive change in their communities? This paper draws on interviews with leaders of successful Aboriginal organisations to understand the factors behind the successes that they are ...
Janet Hunt, Hunt, Janet
core
Background: Patient-reported outcome measures (PROMs) provide patients with a platform to report on healthcare services and interventions, including the management of diabetes and other chronic diseases.
Alicia Burgess +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Paraoxonase 1 (PON1) has been reported to be associated with proteinuria in subjects with type 2 diabetes mellitus (T2DM). Plasma cystatin C is more accurate than creatinine for identifying stage 3 kidney disease in T2DM.
Philip W. Connelly +7 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Aboriginal employment, native title and regionalism [PDF]
The recommendations of the Royal Commission into Aboriginal Deaths in Custody identified tourism as a potential source of private sector employment and enterprise development for Aboriginal people. The question arises as to how realistic this expectation
Finlayson, Julie
core
Background The siloed nature of the health and social service system threatens access for clients engaging numerous organisations. Many Aboriginal and Torres Strait Islander people face adverse circumstances which contribute to multiple health and social
Anna P. Dawson +22 more
doaj +1 more source

