Results 81 to 90 of about 91,089 (313)
Healthcare in Low-resource SettingsIndigenous people often have poor health due to a lack of access to health care. We studied healthcare-seeking behaviors and associated factors of Orang Asli populations living in remote hilly areas of Peninsular Malaysia.
Danaletchumy Ganesan +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Money, business and culture: Issues for Aboriginal economic policy [PDF]
, 1995 A central issue facing policy makers is how to meet principles of equity and social justice in access to economic benefits for Australia’s diverse regional, ethnic and Indigenous populations, while at the same time ensuring broad national goals of ...
Martin, D. F
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Nature and Science of Sleep, 2020 Sumit Mehra,1,2 Ram H Ghimire,1 Joy J Mingi,3,4 Monica Hatch,1 Himanshu Garg,1 Robert Adams,5 Subash S Heraganahally1,3 1Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia; 2Department of ...
Mehra S +6 more
doaj
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Appropriate income support for Aboriginal Australians: options for the 1990s [PDF]
, 1991 This paper focuses specifically on income support options for Aboriginal Australians, and an attempt is made, for analytical purposes, to isolate income from employment issues. Particular attention is paid to the Aboriginal Employment Development Policy (
Altman, Jon
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Description of disadvantage: the households of Aboriginal children
, 1987 A description of the households in which Aboriginal children and young people live is of considerable importance to community and government organizations providing services or policy advice, particularly in education. This is because Aboriginal children
Gray, Alan
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Aboriginal health and institutional reform within Australian federalism [PDF]
, 1996 This paper examines relationships between institutional reform within Australian federalism and Aboriginal health, both historically and in prospect. It begins with a brief historical analysis of government involvement in the general health arena within ...
Anderson, Ian, Sanders, Will
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