Results 71 to 80 of about 107,451 (261)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
K@ta: A Biannual Publication on the Study of Language and Literature, 2022 The dichotomic concept of space between white and Aboriginal Australians has been widely used in the colonial discourse. Through The Secret River, Grenville dismantles the binary oppositions that serves as the main strategy for colonization.
Sri Sumaryani, Zuhrul Anam
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Respecting Aboriginal Parents’ Involvement in their Children’s Learning
Educação & Realidade, 2020 In Australia (and arguably in many other countries) parent involvement in their child’s learning is dominated by Western notions of learning, education, pedagogy and knowledge.
Valerie Harwood, Nyssa Murray
doaj
Tropical Medicine and Infectious Disease, 2018 The impacts of free-roaming canids (domestic and wild) on public health have long been a concern in Australian Indigenous communities. We investigated the prevalence of zoonotic helminth diseases in dogs and sympatric dingoes, and used radio telemetry to
Felicity A. Smout +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Aboriginal socioeconomic change in the Northern Territory, 1986-1991 [PDF]
, 1993 The formation and evaluation of Aboriginal economic policy is heavily dependent upon data from the five-yearly census of population to establish the relative economic standing of Aboriginal people. This paper provides the first opportunity to assess some
Taylor, John
core
Funding allocations to Aboriginal people: the Western Australia case [PDF]
, 1991 This paper attempts to identify the sources of special funding in Aboriginal affairs in Western Australia and how these allocations are spent. First, an assessment is made of the funds allocated by each level of government, Commonwealth, State and local;
Arthur, Bill (W S)
core +1 more source