Results 41 to 50 of about 42,666 (262)

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Relationship between consanguineous marriage and spontaneous abortion and stillbirth

Payesh, 2018
Objective (s): spontaneous abortion and stillbirth has always been a devastating experience for the mother and of concern in clinical practice. Since consanguineous marriage is common in Iran, high rates of congenital malformations and genetic diseases ...
Mehri Shams Ghahfarokhi
doaj  

DDN gene downregulation in endometrium: a potential immune-mediated link between bipolar disorder and spontaneous abortion revealed by Mendelian randomization and bioinformatics

Beni-Suef University Journal of Basic and Applied Sciences
Background Spontaneous abortion, affecting over 20% of pregnancies, presents significant physical and psychological burdens. While chromosomal aneuploidy and environmental factors contribute to its etiology, the role of maternal genetic and psychiatric ...
Jian Tang, Zhixin Xu, Lingling Yang, Qiong Zou   +3 more
doaj   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Comparison of food intake and body mass index before pregnancy between women with spontaneous abortion and women with successful pregnancy [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2017
Introduction:Spontaneous abortion or pregnancy loss is defined as the natural death of fetus before 20th weeks of pregnancy. There is a possibility that food intake is related to spontaneous abortion.
Shirin Amini, Sima Jafarirad, Houra Mohseni, Hajar Ehsani, Ladan Hejazi, Nahid Feghhi   +5 more
doaj   +1 more source

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

Epilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire, Elise Collard, Abigail Niyibizi, Natasha N. Kumar, Enrique Germany Morrison, Javier Chavez Cerda, Ayse S. Dereli, Riem El Tahry   +7 more
wiley   +1 more source

Differences In Serum IL-6 Levels Between First-Trimester Normal Pregnancy and Spontaneous Abortion

Andalas Obstetrics and Gynecology Journal
Objectives: In spontaneous abortion cases without previously known predisposing factors, an increase proinflammatory cytokines, especially interleukin 6 (IL-6), found in local and systemic specimens compared to normal 1st -trimester pregnancies ...
Vella Amalia, Bobby Indra Utama, Dessy Arisanty, Nelmi Silvia   +3 more
doaj   +1 more source

Increased Circulating Levels of Tissue-Type Plasminogen Activator Are Associated with the Risk of Spontaneous Abortion During the First Trimester of Pregnancy

Diagnostics, 2020
Spontaneous abortion is a common complication in early pregnancy, with an incidence of around 20%. Ultrasound scan and measurement of human chorionic gonadotropin are used to identify patients at risk of spontaneous abortion; however, there is a clinical
Lara J. Monteiro, Manuel Varas-Godoy, Stephanie Acuña-Gallardo, Paula Correa, Gianluca Passalacqua, Max Monckeberg, Gregory E. Rice, Sebastián E. Illanes   +7 more
doaj   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source