Results 51 to 60 of about 692,453 (299)

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

Relationship between consanguineous marriage and spontaneous abortion and stillbirth

Payesh, 2018
Objective (s): spontaneous abortion and stillbirth has always been a devastating experience for the mother and of concern in clinical practice. Since consanguineous marriage is common in Iran, high rates of congenital malformations and genetic diseases ...
Mehri Shams Ghahfarokhi
doaj  

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

DDN gene downregulation in endometrium: a potential immune-mediated link between bipolar disorder and spontaneous abortion revealed by Mendelian randomization and bioinformatics

Beni-Suef University Journal of Basic and Applied Sciences
Background Spontaneous abortion, affecting over 20% of pregnancies, presents significant physical and psychological burdens. While chromosomal aneuploidy and environmental factors contribute to its etiology, the role of maternal genetic and psychiatric ...
Jian Tang, Zhixin Xu, Lingling Yang, Qiong Zou   +3 more
doaj   +1 more source

Unintended Pregnancies and Breastfeeding Studies during Central Nervous System Drug Development: How Are they Handled, Is There Room for Improvement?

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant and breastfeeding individuals are routinely excluded from clinical drug development, creating persistent evidence gaps in pharmacology, safety, and dosing. Despite mandatory contraception and pregnancy testing, unintended pregnancies occur, particularly during the development of central nervous system (CNS) medicines used by women of ...
Sam Schoenmakers, Charlotte Bakker, Alexandra Ganev, Florence Butlen‐Ducuing, Corinne S. de Vries   +4 more
wiley   +1 more source

Abortion services in South Africa : challenges and barriers to safe abortion care : health care providers' perspectives [PDF]

, 2010
Includes bibliographical references (leaves 199-213).Unsafe abortion is a preventable phenomenon and continues to be a major public health problem in many countries especially in the developing world.
Harries, Jane
core   +1 more source

Differences In Serum IL-6 Levels Between First-Trimester Normal Pregnancy and Spontaneous Abortion

Andalas Obstetrics and Gynecology Journal
Objectives: In spontaneous abortion cases without previously known predisposing factors, an increase proinflammatory cytokines, especially interleukin 6 (IL-6), found in local and systemic specimens compared to normal 1st -trimester pregnancies ...
Vella Amalia, Bobby Indra Utama, Dessy Arisanty, Nelmi Silvia   +3 more
doaj   +1 more source

Exploring Cultural and Individual Differences in the Hierarchy of Moral Concern: Evidence From Student Samples Across 41 Cultural Groups

European Journal of Social Psychology, EarlyView.
ABSTRACT Many important historical and contemporary ethical debates (e.g., on slavery, abortion and environmental protection) reflect disagreements about what we owe to different groups of individuals. Recent work in moral psychology has uncovered a seemingly replicable hierarchy of moral concern, but these studies were conducted in a few countries ...
Işıl Ayça Akkuş, Charlie R. Crimston, Kelly Kirkland, Brock Bastian, Bastian Jaeger   +4 more
wiley   +1 more source

Antioxidant Defenses, Oxidative Stress Responses, and Apoptosis Modulation in Spontaneous Abortion: An Immunohistochemistry Analysis of First-Trimester Chorionic Villi

Life
Oxidative stress (OS) and apoptosis are critical factors in placental development and function. Their interplay influences trophoblast proliferation, differentiation, and invasion, as well as vascular development. An imbalance between these processes can
Ioana Vornic, Alexandru Nesiu, Ana Maria Ardelean, Oana Cristina Todut, Victoria Cristina Pasare, Cristina Onel, Ionuț Daniel Raducan, Cristian George Furau   +7 more
doaj   +1 more source

Spontaneous Abortion Cases with Fetal Chromosomal Aneuploidy.

, 2013
Spontaneous Abortion Cases with Fetal Chromosomal Aneuploidy.
You Jung Han (195038), Min Hyoung Kim (283284), Hyun Mee Ryu (195047), So Yeon Park (195028), Moon Young Kim (195043), Ji Hyae Lim (195020), Da Eun Lee (283285), Jung Yeol Han (283286)   +7 more
core   +1 more source