Results 71 to 80 of about 42,666 (262)

De‐escalating radical surgery for select FIGO Stage I cervical cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Four recent prospective trials demonstrated that de‐escalation of radical surgery for select patients with apparent low‐risk, FIGO Stage I cervical cancer does not compromise cancer‐related survival but does improve quality of life and provide the opportunity to preserve fertility.
Sara Moufarrij, Rene Pareja, Angélica Fletcher, Sarikapan Wilailak, Nadeem R. Abu‐Rustum, on behalf of the FIGO Committee on Women's Cancer   +5 more
wiley   +1 more source

Advising on Antidepressant Use in Pregnancy: Are We All on the Same Page? [PDF]

Asia Pac Psychiatry
ABSTRACT Purpose Perinatal mood disorders are associated with adverse maternal and neonatal outcomes and affect 15%–20% of pregnant people. Guidelines recommend SSRIs when non‐pharmacological therapies are ineffective, yet antenatal depression remains undertreated.
Broughton LC, Hughes N, Zeng J, Smith A.
europepmc   +2 more sources

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

iMeta, EarlyView.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang, Hongli Zhao, Xinyi Ding, Haoling Zhang, Yadong Guo, Yiming Ma, Lingyi Cai, Qingnan Fan, Ruisi Peng, Fuyuan Yang, Doblin Sandai, Xianling Cao, Jiali Yao, Wenyi Wang, Zhiheng Lin, Wangzheqi Zhang, Jialin He, Aihua Zhang, Xiaoxuan Zhao   +18 more
wiley   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Study of Chromosomal Abnormalities in Couples with Recurrent Spontaneous Abortions (RSA) in Ardabil Province

Journal of Ardabil University of Medical Sciences, 2018
Background & objectives: The spontaneous abortion, loss of the fetus until the twentieth week of pregnancy, is one of the most common medical problems in reproductive age.
Ziba Jahani, Seyyed saeid Hosseini Asl, Homa Akhavan   +2 more
doaj  

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Can Complete Blood Count Parameters Analyzed in Early Pregnancy Predict Threatened Abortion and Spontaneous Abortion: A Retrospective Study

Hamidiye Medical Journal
Background: To evaluate whether first-trimester complete blood count (CBC) parameters predict the risk of spontaneous abortion and threatened abortion. Materials and Methods: We retrospectively analyzed 90 pregnant women who presented to our hospital in
Orhan Ay, Fethiye Şahin, Ali Acar, Pelin Bahçeci, Deniz Taşkıran   +4 more
doaj   +1 more source

Complaints Involving Sonographers: What Three Decades of Cases From A Public New Zealand Database Can Teach Us

Journal of Medical Radiation Sciences, EarlyView.
Health consumer complaints to the New Zealand Health and Disability Commissioner involving sonographers are rare, totalling 15 in the last 31 years and averaging 1.5 cases per year over the last decade. A large proportion of complaints involve an undetected finding, obstetric examination and private setting.
Martin Necas, Claire Calver, Alex Hill, Danielle Mourits, Sarah Park, Carla Smith   +5 more
wiley   +1 more source

The role of Th17/Treg-mediated immunoregulation in abortion mice

International Journal of Immunopathology and Pharmacology, 2018
In the study, we investigated the immune factors related to T helper 17 (Th17) cells and T regulatory (Treg) cells in spontaneous abortion mice. The expression of Th17 was analyzed by interleukin (IL)-6, IL-17A secretion, RAR-related orphan receptor γt ...
Ning Li, Qinglan Qu, Qian Yan
doaj   +1 more source