Clinical‐Stage Nanatinostat Triggers Productive Epstein‐Barr Virus Lytic Replication
ABSTRACT A phase 1b/2 study of the all‐oral “kick‐and‐kill” combo nanatinostat + valganciclovir (nana‐val) showed a ~40% overall response rate in patients with relapsed/refractory Epstein‐Barr virus (EBV)‐associated lymphomas. Despite the promising results in these difficult‐to‐treat cancers, there is little known about the effects of nanatinostat on ...
Ibukun A. Akinyemi +6 more
wiley +1 more source
The predictive value of neutrophil to lymphocyte ratio for abortion: a systematic review and meta-analysis. [PDF]
Wang M, Yue R, Xi J, Yan F.
europepmc +1 more source
Bisoprolol Treatment and Adherence in Pediatric Patients With Genotype‐Positive Long QT Syndrome
LQTS is commonly treated with non‐selective beta‐blockers. In this study on Finnish pediatric patients with genotype positive LQTS1 or LQTS2, most with a Finnish founder mutation, the beta‐1‐selective bisoprolol was the most commonly used beta‐blocker with good adherence, effective heart rate control, and no cardiac events observed during follow‐up ...
Eemil Taipalus +4 more
wiley +1 more source
Gu Ben An Tai decoction combined with dydrogesterone for early threatened abortion secondary to spleen and kidney deficiency: a retrospective observational study. [PDF]
Li X, Wang Y, Su Z, Pei L, Li Y, Wang C.
europepmc +1 more source
Construction and Validation of a Nomogram Model for Stress Urinary Incontinence of Late Pregnancy
ABSTRACT Objective To establish and validate a nomogram model for stress urinary incontinence of late pregnancy and then evaluate its effectiveness. Design Single‐center cross‐sectional study. Methods From January 2025 to June 2025, 414 pregnant women in the late stage of pregnancy who established medical records at a tertiary obstetrics and ...
Shanshan Shan +6 more
wiley +1 more source
ABSTRACT Background Transabdominal cervical cerclage (TACC) may be used for those at very high risk of spontaneous preterm birth, where transvaginal cerclage has been ineffective previously or is not possible. High‐quality randomised evidence supports the use of this relatively uncommon procedure, but there is no published experience of its use in ...
Sarah Latus +5 more
wiley +1 more source
Experiences and Perceptions of Doctors, Nurses, and Midwives Providing Abortion Care in Australia: A Scoping Review. [PDF]
Edmondson K +3 more
europepmc +1 more source
Reproductive outcomes in women with Hodgkin's lymphoma in a Danish fertility preservation cohort
The risk of premature ovarian insufficiency increases with the intensity of alkylating chemotherapy. In general, fertility outcomes were favorable, but chances of live birth decreased with increased intensity of alkylating chemotherapy. Ovarian tissue transplantation enabled natural conception in women with premature ovarian insufficiency, supporting ...
Lotte Berdiin Colmorn +4 more
wiley +1 more source
Factors associated with preterm birth and low birth weight among infants with congenital heart disease in Changsha City, China, 2022-2024. [PDF]
Fu J +6 more
europepmc +1 more source
Preterm birth is associated with substantial neonatal morbidity and mortality. We evaluated whether universal cervical length screening with ultrasound, followed by progesterone therapy for women with a short cervix, has the potential to reduce the incidence of preterm birth.
Mira Zethelius +11 more
wiley +1 more source

