Results 21 to 30 of about 131,503 (247)
Background: Lymphoid-tyrosine-phosphatase which is encoded by the protein tyrosine phosphatase non-receptor 22 (PTPN22) gene plays a pivotal role in the regulation of immune responses by dephosphorylating several signaling intermediates of immune cells ...
Fateme Khanbarari +3 more
doaj +1 more source
Abortion is legal in every state of Australia, yet access to abortion over 20 weeks gestation is not universally guaranteed. Patients with indications outside of maternal medicine or fetal abnormalities experience particular challenges, including ...
C. McDonald +3 more
doaj +1 more source
Background For women seeking permanent contraception, there are a variety of options available including surgical techniques such as tubal ligation or bilateral salpingectomy, in-clinic procedures such as hysteroscopic techniques using micro-inserts, or ...
Rebecca Gormley +2 more
doaj +1 more source
Background: Primary ovarian insufficiency (POI) is a rare disease clinically characterized by ovarian follicles depletion or dysfunction and menopause before the age of 40 yr as the cut-off age for POI.
Farzaneh Sadat Eshaghi +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder that negatively influences oocyte developmental competence. In vitro maturation (IVM) is an approach to reduce complications in the treatment of PCOS-related infertility.
Mohammad Hossein Fakher Baheri +3 more
doaj +1 more source
Background High concentrations of NEFA relative to a defined reference or ‘cut‐point’ values before calving can predict the risk of specific or collective periparturient disease events.
Samuel Kia, Mehrdad Mohri, Hesam A Seifi
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Abortion is common. Data on abortion rates are inexact but can be used to explore trends. Globally, the estimated rate in the period 2010-2014 was 35 abortions per 1000 women (aged 15-44 years), five points less than the rate of 40 for the period 1990-1994.
S. Cameron +12 more
openaire +3 more sources
Objective To evaluate the sensitivity of the 2023 ACR/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS), and to assess their ability to identify patients at risk of future pregnancy complications.
Francesca Ruffilli +10 more
wiley +1 more source

