Results 41 to 50 of about 13,281 (169)

Theileria and Babesia Infections in Sheep and Goats With Abortion Histories in East Azerbaijan Province, Northwest Iran [PDF]

open access: yesArchives of Razi Institute
Introduction: Theileria and Babesia belong to a group of protozoan parasites known as Apicomplexa within the Piroplasmida order. Both Theileria and Babesia disrupt normal hematological functions in their respective hosts, causing hypoxia, anemia and ...
Parisa Shahbazi   +7 more
doaj   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

Comparing the advantages, disadvantages and diagnostic power of different non-invasive pre-implantation genetic testing: A literature review

open access: yesInternational Journal of Reproductive BioMedicine
To improve embryo transfer success and increase the chances of live birth in assisted reproductive methods, there is a growing demand for the use of pre-implantation genetic testing (PGT).
Noorodin Karami   +6 more
doaj   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

open access: yesAdvanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang   +7 more
wiley   +1 more source

The possible regulatory role of miR-4463 and its target gene CYP19A1 on the ovarian response in the women with diminished ovarian reserve: A case-control study

open access: yesInternational Journal of Reproductive BioMedicine
Background: Diminished ovarian reserve (DOR) is a condition that affects fertility by reducing the reproductive potential of the ovary. The altered expression profile of cumulus cells (CCs) can negatively affect the quality and quantity of oocytes in the
Azam Yazdanian   +4 more
doaj   +1 more source

Meiotic gene expression of STAG3 and DMC1 in blood: A novel non-invasive biomarker approach for diminished ovarian reserve: A case-control study

open access: yesInternational Journal of Reproductive BioMedicine
Background: Diminished ovarian reserve (DOR) is a major cause of female infertility, marked by reduced oocyte quantity and quality. STAG3 and DMC1 are meiosis-specific genes essential for chromosomal integrity and homologous recombination.
Khosro Namjoo   +5 more
doaj   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

Bovine salmonellosis in Northeast of Iran: Frequency, genetic fingerprinting and antimicrobial resistance patterns of Salmonella spp.

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
Objective: To evaluate serovar and antimicrobial resistance patterns of Salmonella spp isolated from healthy, diseased and necropsied cows and calves in this observational study.
Hessam A. Halimi   +2 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

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