Results 41 to 50 of about 131,503 (247)

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Comparing the advantages, disadvantages and diagnostic power of different non-invasive pre-implantation genetic testing: A literature review

International Journal of Reproductive BioMedicine
To improve embryo transfer success and increase the chances of live birth in assisted reproductive methods, there is a growing demand for the use of pre-implantation genetic testing (PGT).
Noorodin Karami, Farzaneh Iravani, Sareh Bakhshandeh Bavarsad, Samira Asadollahi, Seyed Mehdi Hoseini, Fateme Montazeri, Seyed Mehdi Kalantar   +6 more
doaj   +1 more source

The Necessity of Dynamic Workflow Managers for Advancing Self‐Driving Labs and Optimizers

Advanced Intelligent Discovery, EarlyView.
We assess the maturity and integration readiness of key methodologies for Materials Acceleration Platforms, highlighting the need for dynamic workflow managers. Demonstrating this, we integrate PerQueue into a color‐mixing robot, showing how flexible orchestration improves coordination and optimization.
Simon K. Steensen, Patrick W. V. Butler, Jesper R. Pedersen, Nis Fisker‐Bødker, Tejs Vegge, Jin Hyun Chang, Ivano E. Castelli   +6 more
wiley   +1 more source

Exploring pharmacy provision of medication abortion pills in Nepal: a mixed-methods study of pharmacy workers’ knowledge and practices

Sexual and Reproductive Health Matters
In Nepal, pharmacists are legally permitted to dispense medication abortion drugs with a prescription but provision of mifepristone/misoprostol without a prescription is prohibited. However, one in five Nepalese women seeking medication abortion pills do
Nished Rijal, Angel M. Foster
doaj   +1 more source

Bovine salmonellosis in Northeast of Iran: Frequency, genetic fingerprinting and antimicrobial resistance patterns of Salmonella spp.

Asian Pacific Journal of Tropical Biomedicine, 2014
Objective: To evaluate serovar and antimicrobial resistance patterns of Salmonella spp isolated from healthy, diseased and necropsied cows and calves in this observational study.
Hessam A. Halimi, Hesam A. Seifi, Mehrnaz Rad   +2 more
doaj   +1 more source

FastCat: Autonomous Discovery of Multielement Layered Double Hydroxide Alloy Catalysts for Alkaline Oxygen Evolution Reaction

Advanced Intelligent Discovery, EarlyView.
A machine learning‐guided self‐driving laboratory screened over 500 nickel‐based layered double‐hydroxide catalysts for alkaline oxygen evolution. Out of the eight metals, the robot uncovered a quaternary Ni–Fe–Cr–Co catalysts requiring only 231 mV overpotential to reach 20 mA cm−2.
Nis Fisker‐Bødker, Enzo Raffaele Moretti, Jin Hyun Chang, Tejs Vegge   +3 more
wiley   +1 more source

The possible regulatory role of miR-4463 and its target gene CYP19A1 on the ovarian response in the women with diminished ovarian reserve: A case-control study

International Journal of Reproductive BioMedicine
Background: Diminished ovarian reserve (DOR) is a condition that affects fertility by reducing the reproductive potential of the ovary. The altered expression profile of cumulus cells (CCs) can negatively affect the quality and quantity of oocytes in the
Azam Yazdanian, Marzieh Lotfi, Fateme Montazeri, Saeideh Dashti, Mohammad Hasan Sheikhha   +4 more
doaj   +1 more source

Bayesian Optimisation for the Experimental Sciences: A Practical Guide to Data‐Efficient Optimisation of Laboratory Workflows

Advanced Intelligent Systems, EarlyView.
This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He, Martin Singull, T. Jesper Jacobsson   +2 more
wiley   +1 more source

Entropy‐Guided Convolutional Neural Network Classification of Sensor Signals for Real‐Time Surface Quality Monitoring in Direct Laser Interference Patterning

Advanced Intelligent Systems, EarlyView.
Neural‐network pipeline for real‐time DLIP surface‐quality monitoring: spectral entropy of WLI topographies is used to generate interpretable K‐means labels, which are transferred to time‐resolved photodiode traces. A compact dual‐input 1D‐CNN (signal + laser parameters) learns discriminative spatiotemporal features and predicts “OK/NOK” surface ...
Marcelo Daniel Sallese, Ignacio Tabares, Wei Wang, Marcos Soldera, Andrés Fabián Lasagni   +4 more
wiley   +1 more source

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

American Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman, Thomas L. Marsh   +1 more
wiley   +1 more source